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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK1
All Species:
16.06
Human Site:
T386
Identified Species:
29.44
UniProt:
Q99986
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99986
NP_003375.1
396
45476
T386
Q
T
E
E
A
I
Q
T
R
S
R
T
R
K
R
Chimpanzee
Pan troglodytes
XP_510157
396
45456
T386
Q
T
E
E
A
I
Q
T
R
S
R
T
R
K
R
Rhesus Macaque
Macaca mulatta
XP_001102618
396
45467
T386
Q
T
E
E
A
I
Q
T
R
S
R
T
R
K
R
Dog
Lupus familis
XP_547970
395
44398
A386
G
C
T
H
V
K
A
A
R
A
V
C
A
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80X41
440
49722
T386
Q
V
Q
E
A
A
Q
T
R
S
V
E
S
Q
G
Rat
Rattus norvegicus
P97633
325
37477
G316
A
A
S
S
S
G
Q
G
Q
Q
A
Q
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
S385
R
L
G
E
F
N
F
S
H
D
P
N
H
C
L
Chicken
Gallus gallus
NP_001006485
413
46937
S385
P
E
K
K
K
P
A
S
S
K
A
V
A
T
R
Frog
Xenopus laevis
NP_001080108
438
49973
T424
N
R
E
D
F
E
E
T
E
S
Q
R
K
A
L
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
E387
R
R
A
P
Q
K
K
E
V
N
G
A
K
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
E398
E
D
D
E
E
E
E
E
K
S
H
R
K
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
R392
R
A
A
P
P
K
K
R
T
A
S
A
K
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23292
546
62061
Q476
T
S
Y
E
A
Y
Q
Q
Q
T
Q
Q
K
Y
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83.8
N.A.
76.8
29
N.A.
66.1
70.2
47.2
59.2
N.A.
31
N.A.
N.A.
39.7
Protein Similarity:
100
99.7
98.9
88.1
N.A.
83.4
46.4
N.A.
73
81.5
59.3
72.4
N.A.
43.7
N.A.
N.A.
56
P-Site Identity:
100
100
100
6.6
N.A.
46.6
6.6
N.A.
6.6
6.6
20
6.6
N.A.
20
N.A.
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
60
20
N.A.
20
26.6
46.6
33.3
N.A.
53.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
16
0
39
8
16
8
0
16
16
16
16
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
8
8
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
8
31
54
8
16
16
16
8
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
16
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
8
0
8
0
0
8
0
0
8
8
% G
% His:
0
0
0
8
0
0
0
0
8
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
24
16
0
8
8
0
0
39
39
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% N
% Pro:
8
0
0
16
8
8
0
0
0
0
8
0
0
8
8
% P
% Gln:
31
0
8
0
8
0
47
8
16
8
16
16
0
8
8
% Q
% Arg:
24
16
0
0
0
0
0
8
39
0
24
16
24
0
31
% R
% Ser:
0
8
8
8
8
0
0
16
8
47
8
0
8
0
0
% S
% Thr:
8
24
8
0
0
0
0
39
8
8
0
24
8
8
24
% T
% Val:
0
8
0
0
8
0
0
0
8
0
16
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _