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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK1
All Species:
22.73
Human Site:
S158
Identified Species:
41.67
UniProt:
Q99986
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99986
NP_003375.1
396
45476
S158
R
K
T
V
L
Q
L
S
L
R
I
L
D
I
L
Chimpanzee
Pan troglodytes
XP_510157
396
45456
S158
R
K
T
V
L
Q
L
S
L
R
I
L
D
I
L
Rhesus Macaque
Macaca mulatta
XP_001102618
396
45467
S158
R
K
T
V
L
Q
L
S
L
R
I
L
D
I
L
Dog
Lupus familis
XP_547970
395
44398
S158
R
K
T
V
L
Q
L
S
L
R
I
L
D
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80X41
440
49722
S158
R
K
T
V
L
Q
L
S
L
R
I
L
D
I
L
Rat
Rattus norvegicus
P97633
325
37477
L92
Y
N
V
L
V
M
D
L
L
G
P
S
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
S157
R
K
T
V
L
Q
L
S
L
R
I
L
D
I
L
Chicken
Gallus gallus
NP_001006485
413
46937
G157
H
K
T
V
L
Q
L
G
L
R
I
L
D
I
L
Frog
Xenopus laevis
NP_001080108
438
49973
G147
M
Q
R
V
M
Q
L
G
I
C
M
L
D
V
L
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
G159
R
K
L
V
L
Q
L
G
L
R
L
L
D
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
A164
E
G
T
V
Y
R
L
A
I
Q
M
L
D
V
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
A151
P
G
L
V
F
A
L
A
I
Q
I
L
D
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23292
546
62061
M179
V
V
Q
V
A
V
Q
M
I
T
L
I
E
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83.8
N.A.
76.8
29
N.A.
66.1
70.2
47.2
59.2
N.A.
31
N.A.
N.A.
39.7
Protein Similarity:
100
99.7
98.9
88.1
N.A.
83.4
46.4
N.A.
73
81.5
59.3
72.4
N.A.
43.7
N.A.
N.A.
56
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
86.6
40
80
N.A.
33.3
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
86.6
73.3
86.6
N.A.
73.3
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
85
8
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
0
0
0
0
24
0
8
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
31
0
62
8
0
62
0
% I
% Lys:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
16
8
62
0
85
8
70
0
16
85
8
0
85
% L
% Met:
8
0
0
0
8
8
0
8
0
0
16
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
8
8
0
0
70
8
0
0
16
0
0
0
0
0
% Q
% Arg:
54
0
8
0
0
8
0
0
0
62
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
47
0
0
0
8
0
8
0
% S
% Thr:
0
0
62
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
8
8
8
93
8
8
0
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _