KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TEP1
All Species:
13.64
Human Site:
T599
Identified Species:
42.86
UniProt:
Q99973
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99973
NP_009041.2
2627
290490
T599
T
L
M
R
R
I
L
T
R
N
E
K
N
R
P
Chimpanzee
Pan troglodytes
XP_001137917
2627
290911
T599
T
L
M
R
R
I
L
T
R
N
E
K
N
R
P
Rhesus Macaque
Macaca mulatta
XP_001092046
2724
300526
T683
T
L
M
R
R
I
L
T
R
S
D
K
N
R
P
Dog
Lupus familis
XP_539672
2603
283765
S574
K
L
M
R
L
I
M
S
R
N
A
K
Q
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P97499
2629
291441
I605
T
L
M
K
R
I
M
I
R
N
S
K
K
N
R
Rat
Rattus norvegicus
O08653
2629
291690
I609
T
L
M
K
R
I
M
I
R
N
S
K
K
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002660903
2542
286668
K588
D
I
I
R
D
I
L
K
K
L
P
K
T
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789472
2666
295519
S606
S
E
L
P
Y
D
I
S
I
L
N
R
Y
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
89.6
71.3
N.A.
75.5
74.9
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
N.A.
N.A.
N.A.
29.4
Protein Similarity:
100
99
91.8
80.2
N.A.
84.6
84.4
N.A.
N.A.
N.A.
N.A.
49.4
N.A.
N.A.
N.A.
N.A.
49
P-Site Identity:
100
100
86.6
46.6
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
60
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
13
13
0
0
0
0
13
0
0
13
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
25
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
13
0
0
88
13
25
13
0
0
0
0
13
0
% I
% Lys:
13
0
0
25
0
0
0
13
13
0
0
88
25
0
38
% K
% Leu:
0
75
13
0
13
0
50
0
0
25
0
0
0
0
0
% L
% Met:
0
0
75
0
0
0
38
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
63
13
0
38
13
0
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
38
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
0
0
0
63
63
0
0
0
75
0
0
13
0
63
25
% R
% Ser:
13
0
0
0
0
0
0
25
0
13
25
0
0
0
0
% S
% Thr:
63
0
0
0
0
0
0
38
0
0
0
0
13
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _