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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC2
All Species:
18.48
Human Site:
Y494
Identified Species:
36.97
UniProt:
Q99958
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99958
NP_005242.1
501
53719
Y494
L
Y
R
H
A
A
P
Y
S
Y
D
C
T
K
Y
Chimpanzee
Pan troglodytes
XP_523450
676
72856
Y669
L
Y
R
H
A
A
P
Y
S
Y
D
C
T
K
Y
Rhesus Macaque
Macaca mulatta
XP_001085933
501
53645
Y494
L
Y
R
H
A
A
P
Y
S
Y
D
C
T
K
Y
Dog
Lupus familis
XP_860948
505
53975
Y498
L
Y
R
H
A
A
P
Y
S
Y
D
C
T
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61850
494
52856
Rat
Rattus norvegicus
NP_001095150
494
52836
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990469
468
50649
Frog
Xenopus laevis
Q9PVY9
465
51595
Zebra Danio
Brachydanio rerio
NP_571803
476
52154
F469
I
Y
R
T
S
G
A
F
V
Y
D
C
S
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
S487
L
G
Q
L
G
Q
L
S
N
L
S
H
Y
R
P
Honey Bee
Apis mellifera
XP_001121752
495
55049
C486
V
K
Q
E
W
I
P
C
T
E
D
L
A
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
Y512
M
Y
P
P
S
A
H
Y
S
Y
D
C
S
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.1
95.8
N.A.
89.6
90
N.A.
N.A.
66.8
65.8
52.8
N.A.
32.8
31.1
N.A.
37.5
Protein Similarity:
100
52.9
99.4
96.4
N.A.
92.4
92.8
N.A.
N.A.
72.4
75.6
65.8
N.A.
42.7
43.3
N.A.
49.5
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
N.A.
0
0
40
N.A.
6.6
20
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
0
0
N.A.
N.A.
0
0
73.3
N.A.
26.6
40
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
42
9
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
50
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
34
0
0
9
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
59
0
% K
% Leu:
42
0
0
9
0
0
9
0
0
9
0
9
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
9
9
0
0
42
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
42
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
0
17
0
0
9
42
0
9
0
17
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
0
0
34
0
0
% T
% Val:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
0
0
42
0
50
0
0
9
0
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _