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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC2
All Species:
23.94
Human Site:
Y24
Identified Species:
47.88
UniProt:
Q99958
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99958
NP_005242.1
501
53719
Y24
P
Y
L
S
E
Q
N
Y
Y
R
A
A
G
S
Y
Chimpanzee
Pan troglodytes
XP_523450
676
72856
R36
D
A
N
T
H
G
V
R
P
A
A
P
G
A
A
Rhesus Macaque
Macaca mulatta
XP_001085933
501
53645
Y24
P
Y
L
S
E
Q
N
Y
Y
R
A
A
G
S
Y
Dog
Lupus familis
XP_860948
505
53975
Y24
P
Y
L
S
E
Q
N
Y
Y
R
A
A
G
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61850
494
52856
Y24
P
Y
L
S
E
Q
N
Y
Y
R
A
A
G
S
Y
Rat
Rattus norvegicus
NP_001095150
494
52836
Y24
P
Y
L
S
E
Q
N
Y
Y
R
A
A
G
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990469
468
50649
E21
G
V
V
P
Y
L
S
E
Q
N
Y
Y
R
T
A
Frog
Xenopus laevis
Q9PVY9
465
51595
P18
P
N
A
L
G
V
V
P
Y
L
S
E
Q
N
Y
Zebra Danio
Brachydanio rerio
NP_571803
476
52154
S24
P
Y
I
S
S
D
Q
S
Y
Y
R
A
A
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
A27
A
G
Y
G
S
A
S
A
V
A
A
A
S
S
A
Honey Bee
Apis mellifera
XP_001121752
495
55049
Y27
V
G
M
G
T
P
S
Y
P
G
V
G
A
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
Y30
Q
G
M
A
M
Q
P
Y
H
S
A
A
P
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.1
95.8
N.A.
89.6
90
N.A.
N.A.
66.8
65.8
52.8
N.A.
32.8
31.1
N.A.
37.5
Protein Similarity:
100
52.9
99.4
96.4
N.A.
92.4
92.8
N.A.
N.A.
72.4
75.6
65.8
N.A.
42.7
43.3
N.A.
49.5
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
0
20
33.3
N.A.
20
6.6
N.A.
33.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
20
33.3
46.6
N.A.
26.6
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
9
0
9
0
9
0
17
67
67
17
25
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
42
0
0
9
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
25
0
17
9
9
0
0
0
9
0
9
50
0
9
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
42
9
0
9
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
17
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
42
0
0
9
0
0
0
9
0
% N
% Pro:
59
0
0
9
0
9
9
9
17
0
0
9
9
0
9
% P
% Gln:
9
0
0
0
0
50
9
0
9
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
42
9
0
9
0
0
% R
% Ser:
0
0
0
50
17
0
25
9
0
9
9
0
9
59
0
% S
% Thr:
0
0
0
9
9
0
0
0
0
0
0
0
0
9
0
% T
% Val:
9
9
9
0
0
9
17
0
9
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
9
0
9
0
0
59
59
9
9
9
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _