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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC2
All Species:
6.36
Human Site:
S49
Identified Species:
12.73
UniProt:
Q99958
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99958
NP_005242.1
501
53719
S49
S
G
H
P
E
Q
Y
S
A
G
M
G
R
S
Y
Chimpanzee
Pan troglodytes
XP_523450
676
72856
T61
G
A
E
G
E
L
N
T
F
R
L
Y
R
R
L
Rhesus Macaque
Macaca mulatta
XP_001085933
501
53645
S49
S
G
H
P
E
Q
Y
S
A
G
M
G
R
S
Y
Dog
Lupus familis
XP_860948
505
53975
G49
S
G
H
P
E
Q
Y
G
A
G
M
G
R
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61850
494
52856
G49
S
G
H
P
E
Q
Y
G
A
G
M
G
R
S
Y
Rat
Rattus norvegicus
NP_001095150
494
52836
G49
S
G
H
P
E
Q
Y
G
A
G
M
G
R
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990469
468
50649
E46
S
V
Y
S
G
H
A
E
Q
Y
A
A
G
M
G
Frog
Xenopus laevis
Q9PVY9
465
51595
P43
A
T
P
M
S
V
Y
P
T
H
E
Q
Y
T
Q
Zebra Danio
Brachydanio rerio
NP_571803
476
52154
H49
T
M
Y
S
H
A
A
H
D
Q
Y
P
A
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
Y52
D
Q
Y
S
R
Y
P
Y
S
A
S
A
Y
G
L
Honey Bee
Apis mellifera
XP_001121752
495
55049
P52
Y
A
T
A
A
G
Y
P
V
S
G
I
T
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
P55
E
Q
G
Y
Y
R
H
P
T
Y
S
G
M
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.1
95.8
N.A.
89.6
90
N.A.
N.A.
66.8
65.8
52.8
N.A.
32.8
31.1
N.A.
37.5
Protein Similarity:
100
52.9
99.4
96.4
N.A.
92.4
92.8
N.A.
N.A.
72.4
75.6
65.8
N.A.
42.7
43.3
N.A.
49.5
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
20
20
N.A.
13.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
9
9
9
17
0
42
9
9
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
9
0
9
0
50
0
0
9
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
42
9
9
9
9
0
25
0
42
9
50
9
9
9
% G
% His:
0
0
42
0
9
9
9
9
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
17
% L
% Met:
0
9
0
9
0
0
0
0
0
0
42
0
9
9
17
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
42
0
0
9
25
0
0
0
9
0
9
0
% P
% Gln:
0
17
0
0
0
42
0
0
9
9
0
9
0
9
17
% Q
% Arg:
0
0
0
0
9
9
0
0
0
9
0
0
50
9
0
% R
% Ser:
50
0
0
25
9
0
0
17
9
9
17
0
0
50
0
% S
% Thr:
9
9
9
0
0
0
0
9
17
0
0
0
9
9
0
% T
% Val:
0
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
25
9
9
9
59
9
0
17
9
9
17
0
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _