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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC2
All Species:
22.73
Human Site:
S464
Identified Species:
45.45
UniProt:
Q99958
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99958
NP_005242.1
501
53719
S464
H
R
L
G
I
E
N
S
T
L
G
E
S
Q
V
Chimpanzee
Pan troglodytes
XP_523450
676
72856
S639
H
R
L
G
I
E
N
S
T
L
G
E
S
Q
V
Rhesus Macaque
Macaca mulatta
XP_001085933
501
53645
S464
H
R
L
G
I
E
N
S
T
L
G
E
S
Q
V
Dog
Lupus familis
XP_860948
505
53975
S468
H
R
L
G
M
E
N
S
T
L
G
E
P
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61850
494
52856
S458
H
R
L
G
L
D
N
S
S
L
G
E
S
Q
V
Rat
Rattus norvegicus
NP_001095150
494
52836
S458
H
R
L
G
L
D
N
S
T
L
G
E
S
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990469
468
50649
M432
T
F
P
N
V
R
E
M
F
T
S
H
R
L
G
Frog
Xenopus laevis
Q9PVY9
465
51595
A429
R
L
G
I
E
S
S
A
L
S
E
H
Q
V
S
Zebra Danio
Brachydanio rerio
NP_571803
476
52154
I439
E
M
F
E
S
Q
R
I
G
L
N
N
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
A457
S
V
A
A
A
S
A
A
A
A
A
A
V
I
S
Honey Bee
Apis mellifera
XP_001121752
495
55049
L456
T
Q
S
P
S
C
Q
L
Y
R
P
H
H
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
S482
S
S
A
N
A
N
E
S
C
Q
L
S
M
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.1
95.8
N.A.
89.6
90
N.A.
N.A.
66.8
65.8
52.8
N.A.
32.8
31.1
N.A.
37.5
Protein Similarity:
100
52.9
99.4
96.4
N.A.
92.4
92.8
N.A.
N.A.
72.4
75.6
65.8
N.A.
42.7
43.3
N.A.
49.5
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
N.A.
0
0
20
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
6.6
13.3
26.6
N.A.
6.6
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
17
0
9
17
9
9
9
9
0
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
9
9
34
17
0
0
0
9
50
0
0
0
% E
% Phe:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
50
0
0
0
0
9
0
50
0
0
0
17
% G
% His:
50
0
0
0
0
0
0
0
0
0
0
25
9
0
0
% H
% Ile:
0
0
0
9
25
0
0
9
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
50
0
17
0
0
9
9
59
9
0
0
9
0
% L
% Met:
0
9
0
0
9
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
17
0
9
50
0
0
0
9
9
0
0
0
% N
% Pro:
0
0
9
9
0
0
0
0
0
0
9
0
9
9
0
% P
% Gln:
0
9
0
0
0
9
9
0
0
9
0
0
9
50
0
% Q
% Arg:
9
50
0
0
0
9
9
0
0
9
0
0
9
9
0
% R
% Ser:
17
9
9
0
17
17
9
59
9
9
9
9
50
9
17
% S
% Thr:
17
0
0
0
0
0
0
0
42
9
0
0
0
0
0
% T
% Val:
0
9
0
0
9
0
0
0
0
0
0
0
9
9
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _