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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXC2 All Species: 25.45
Human Site: S337 Identified Species: 50.91
UniProt: Q99958 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99958 NP_005242.1 501 53719 S337 Q C S M R A M S L Y T G A E R
Chimpanzee Pan troglodytes XP_523450 676 72856 S512 Q C S M R A M S L Y T G A E R
Rhesus Macaque Macaca mulatta XP_001085933 501 53645 S337 Q C S M R A M S L Y T G A E R
Dog Lupus familis XP_860948 505 53975 S337 Q C S M R A M S L Y T G A E R
Cat Felis silvestris
Mouse Mus musculus Q61850 494 52856 S336 Q C S M R A M S L Y T G A E R
Rat Rattus norvegicus NP_001095150 494 52836 S336 Q C S M R A M S L Y T G A E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990469 468 50649 S320 S G Q P S G Y S A A C S Q A L
Frog Xenopus laevis Q9PVY9 465 51595 S317 Q S M D T S G S Y Q C T M R A
Zebra Danio Brachydanio rerio NP_571803 476 52154 P327 Q S S V Y S S P C S Q N S I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32027 508 54498 T338 Q S S G H S P T T I S T P H G
Honey Bee Apis mellifera XP_001121752 495 55049 H338 P H G L Q H P H P H S H S I M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780709 519 57235 P365 R I T C S K R P V V S S L N Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.4 99.1 95.8 N.A. 89.6 90 N.A. N.A. 66.8 65.8 52.8 N.A. 32.8 31.1 N.A. 37.5
Protein Similarity: 100 52.9 99.4 96.4 N.A. 92.4 92.8 N.A. N.A. 72.4 75.6 65.8 N.A. 42.7 43.3 N.A. 49.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 13.3 13.3 N.A. 13.3 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 20 33.3 N.A. 33.3 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 50 0 0 9 9 0 0 50 9 9 % A
% Cys: 0 50 0 9 0 0 0 0 9 0 17 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 9 9 0 9 9 0 0 0 0 50 0 0 9 % G
% His: 0 9 0 0 9 9 0 9 0 9 0 9 0 9 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 9 0 0 0 17 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 0 50 0 0 0 9 0 9 % L
% Met: 0 0 9 50 0 0 50 0 0 0 0 0 9 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % N
% Pro: 9 0 0 9 0 0 17 17 9 0 0 0 9 0 0 % P
% Gln: 75 0 9 0 9 0 0 0 0 9 9 0 9 0 9 % Q
% Arg: 9 0 0 0 50 0 9 0 0 0 0 0 0 9 50 % R
% Ser: 9 25 67 0 17 25 9 67 0 9 25 17 17 0 9 % S
% Thr: 0 0 9 0 9 0 0 9 9 0 50 17 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 9 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 9 0 9 50 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _