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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXB1 All Species: 11.21
Human Site: S239 Identified Species: 22.42
UniProt: Q99853 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99853 NP_036314.2 325 34978 S239 S M A S G D Y S A Y G V P L K
Chimpanzee Pan troglodytes XP_528330 432 45477 G342 V P V G P E Y G A F G V P V K
Rhesus Macaque Macaca mulatta XP_001100107 431 45425 G341 V P V G P E Y G A F G V P V K
Dog Lupus familis XP_544707 692 74313 S606 S M A S G D Y S A Y G V P L K
Cat Felis silvestris
Mouse Mus musculus Q64732 325 34990 S239 S M T S G D Y S A Y G V P L K
Rat Rattus norvegicus Q63246 101 12079 Q17 A L S T M A I Q N A P E K K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505655 382 43279 S239 L G A A A E R S P P K I R R R
Chicken Gallus gallus
Frog Xenopus laevis O93529 319 34936 Y234 I S M A N S D Y S V S A Y G V
Zebra Danio Brachydanio rerio NP_571360 297 32927 M213 D S A A P I S M T S S D Y S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32028 372 41705 G256 I D V V E C S G I S R Y P T T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34683 237 26878 F153 P P L L S S L F P N L P P S L
Sea Urchin Strong. purpuratus NP_999797 360 40715 K250 S T D M C C G K S R D S P V C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.3 45.4 46.8 N.A. 99.6 21.2 N.A. 38.2 N.A. 84 80.6 N.A. 37 N.A. 37.5 41.6
Protein Similarity: 100 55.5 55.6 46.8 N.A. 99.6 26.1 N.A. 48.9 N.A. 89.8 83.6 N.A. 49.4 N.A. 51 51.6
P-Site Identity: 100 40 40 100 N.A. 93.3 0 N.A. 13.3 N.A. 0 6.6 N.A. 6.6 N.A. 6.6 13.3
P-Site Similarity: 100 60 60 100 N.A. 93.3 26.6 N.A. 40 N.A. 13.3 13.3 N.A. 6.6 N.A. 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 34 25 9 9 0 0 42 9 0 9 0 0 9 % A
% Cys: 0 0 0 0 9 17 0 0 0 0 0 0 0 0 9 % C
% Asp: 9 9 9 0 0 25 9 0 0 0 9 9 0 0 0 % D
% Glu: 0 0 0 0 9 25 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 17 0 0 0 0 0 % F
% Gly: 0 9 0 17 25 0 9 25 0 0 42 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 0 0 0 9 9 0 9 0 0 9 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 9 0 9 9 42 % K
% Leu: 9 9 9 9 0 0 9 0 0 0 9 0 0 25 9 % L
% Met: 0 25 9 9 9 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 9 9 0 0 0 0 0 % N
% Pro: 9 25 0 0 25 0 0 0 17 9 9 9 67 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 9 9 0 9 9 9 % R
% Ser: 34 17 9 25 9 17 17 34 17 17 17 9 0 17 0 % S
% Thr: 0 9 9 9 0 0 0 0 9 0 0 0 0 9 9 % T
% Val: 17 0 25 9 0 0 0 0 0 9 0 42 0 25 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 42 9 0 25 0 9 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _