KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGDIG
All Species:
27.58
Human Site:
Y177
Identified Species:
60.67
UniProt:
Q99819
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99819
NP_001167.2
225
25098
Y177
Y
G
P
S
A
Q
E
Y
E
F
V
T
P
V
E
Chimpanzee
Pan troglodytes
XP_001171621
242
27108
Y194
Y
G
P
S
A
Q
E
Y
E
F
V
T
P
V
E
Rhesus Macaque
Macaca mulatta
XP_001118456
217
24079
Y169
Y
G
P
S
A
Q
E
Y
E
F
V
T
P
V
E
Dog
Lupus familis
XP_854314
246
26701
Y198
Y
G
P
R
A
Q
E
Y
E
F
V
T
P
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62160
225
25278
Y177
Y
G
P
R
A
Q
E
Y
E
F
V
T
S
V
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515491
219
25235
Y171
Y
G
P
R
A
E
E
Y
E
Y
Q
T
P
L
E
Chicken
Gallus gallus
NP_001074340
204
23256
Y156
Y
G
P
R
A
E
E
Y
E
F
L
T
P
M
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20496
191
21900
Q146
Y
A
P
K
L
E
I
Q
E
Y
K
S
P
N
E
Sea Urchin
Strong. purpuratus
XP_781627
200
22679
H153
Y
G
P
K
T
E
P
H
L
Y
Q
T
P
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFC6
240
27213
Y191
F
S
P
Q
L
E
P
Y
N
H
V
M
P
E
E
Baker's Yeast
Sacchar. cerevisiae
Q12434
202
23120
K154
Y
A
P
N
T
K
T
K
P
F
Y
E
V
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
88.8
69.9
N.A.
79.5
N.A.
N.A.
60.4
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
30.2
41.3
Protein Similarity:
100
87.5
90.6
77.2
N.A.
88.8
N.A.
N.A.
72
69.3
N.A.
N.A.
N.A.
N.A.
N.A.
45.7
58.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
40
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
49.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
64
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
46
64
0
73
0
0
10
0
19
91
% E
% Phe:
10
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% F
% Gly:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
19
0
10
0
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
19
0
0
0
10
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
0
0
0
19
0
% N
% Pro:
0
0
100
0
0
0
19
0
10
0
0
0
82
0
0
% P
% Gln:
0
0
0
10
0
46
0
10
0
0
19
0
0
0
0
% Q
% Arg:
0
0
0
37
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
28
0
0
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
19
0
10
0
0
0
0
73
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
55
0
10
46
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
91
0
0
0
0
0
0
73
0
28
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _