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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGDIG
All Species:
32.12
Human Site:
T181
Identified Species:
70.67
UniProt:
Q99819
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99819
NP_001167.2
225
25098
T181
A
Q
E
Y
E
F
V
T
P
V
E
E
A
P
R
Chimpanzee
Pan troglodytes
XP_001171621
242
27108
T198
A
Q
E
Y
E
F
V
T
P
V
E
E
A
P
R
Rhesus Macaque
Macaca mulatta
XP_001118456
217
24079
T173
A
Q
E
Y
E
F
V
T
P
V
E
E
A
P
R
Dog
Lupus familis
XP_854314
246
26701
T202
A
Q
E
Y
E
F
V
T
P
V
E
E
A
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62160
225
25278
T181
A
Q
E
Y
E
F
V
T
S
V
E
E
A
P
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515491
219
25235
T175
A
E
E
Y
E
Y
Q
T
P
L
E
E
A
P
R
Chicken
Gallus gallus
NP_001074340
204
23256
T160
A
E
E
Y
E
F
L
T
P
M
E
E
A
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20496
191
21900
S150
L
E
I
Q
E
Y
K
S
P
N
E
E
A
P
S
Sea Urchin
Strong. purpuratus
XP_781627
200
22679
T157
T
E
P
H
L
Y
Q
T
P
N
E
E
A
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFC6
240
27213
M195
L
E
P
Y
N
H
V
M
P
E
E
T
T
P
S
Baker's Yeast
Sacchar. cerevisiae
Q12434
202
23120
E158
T
K
T
K
P
F
Y
E
V
E
L
P
E
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
88.8
69.9
N.A.
79.5
N.A.
N.A.
60.4
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
30.2
41.3
Protein Similarity:
100
87.5
90.6
77.2
N.A.
88.8
N.A.
N.A.
72
69.3
N.A.
N.A.
N.A.
N.A.
N.A.
45.7
58.2
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
40
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
49.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
46
64
0
73
0
0
10
0
19
91
82
10
0
10
% E
% Phe:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
19
0
0
0
10
0
10
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
0
19
0
10
0
0
0
82
0
0
10
0
91
0
% P
% Gln:
0
46
0
10
0
0
19
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% R
% Ser:
0
0
0
0
0
0
0
10
10
0
0
0
0
10
28
% S
% Thr:
19
0
10
0
0
0
0
73
0
0
0
10
10
0
0
% T
% Val:
0
0
0
0
0
0
55
0
10
46
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
73
0
28
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _