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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIPEP All Species: 27.27
Human Site: Y628 Identified Species: 46.15
UniProt: Q99797 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99797 NP_005923.2 713 80641 Y628 R F S H L V G Y G A R Y Y S Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090198 713 80564 Y628 R F S H L V G Y G A K Y Y S Y
Dog Lupus familis XP_534532 662 75720 Y577 R F S H L V G Y G A K Y Y S Y
Cat Felis silvestris
Mouse Mus musculus A6H611 711 80834 Y626 R F S H L V G Y G A K Y Y S Y
Rat Rattus norvegicus Q01992 710 80655 Y625 R F S H L V G Y G A K Y Y S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519255 686 77419 Y601 R F S H L V G Y G A K Y Y S Y
Chicken Gallus gallus XP_417136 704 79533 Y620 R F S H L V G Y G A K Y Y S Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344847 700 79903 G615 F S H L I G Y G A K Y Y S Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610183 699 80218 G610 L R F S H L V G Y G A K Y Y A
Honey Bee Apis mellifera XP_396237 696 80078 G612 F S H L V G Y G A K Y Y S Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182998 420 47731 P352 D I L A W D P P F Y M G L T R
Poplar Tree Populus trichocarpa XP_002321840 726 81749 N639 I R F S H L V N Y G A G Y Y S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35999 772 88164 L691 W C G R F G H L F G Y G A T Y
Red Bread Mold Neurospora crassa Q7SDD5 805 91077 L711 W Q G F F G H L V G Y G S T Y
Conservation
Percent
Protein Identity: 100 N.A. 97.9 85.6 N.A. 82.8 83.4 N.A. 77 78.6 N.A. 71.3 N.A. 47.5 46 N.A. 29.1
Protein Similarity: 100 N.A. 98.8 89.4 N.A. 90 89.1 N.A. 85.5 88.5 N.A. 84.4 N.A. 65.7 66 N.A. 43
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. 6.6 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 N.A. 13.3 N.A. 13.3 13.3 N.A. 6.6
Percent
Protein Identity: 34.5 N.A. N.A. N.A. 31.3 29.8
Protein Similarity: 53.8 N.A. N.A. N.A. 50.9 46
P-Site Identity: 6.6 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 13.3 N.A. N.A. N.A. 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 15 50 15 0 8 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 15 50 15 8 15 0 0 0 15 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 29 50 22 50 29 0 29 0 0 0 % G
% His: 0 0 15 50 15 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 15 43 8 0 0 0 % K
% Leu: 8 0 8 15 50 15 0 15 0 0 0 0 8 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 50 15 0 8 0 0 0 0 0 0 8 0 0 0 8 % R
% Ser: 0 15 50 15 0 0 0 0 0 0 0 0 22 50 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 22 0 % T
% Val: 0 0 0 0 8 50 15 0 8 0 0 0 0 0 0 % V
% Trp: 15 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 15 50 15 8 29 65 65 29 65 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _