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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIPEP All Species: 15.76
Human Site: S414 Identified Species: 26.67
UniProt: Q99797 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99797 NP_005923.2 713 80641 S414 P A K G E V W S E D V R K L A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090198 713 80564 S414 P A K G E V W S E D V R K L A
Dog Lupus familis XP_534532 662 75720 C363 P A K G E V W C E D V R K L A
Cat Felis silvestris
Mouse Mus musculus A6H611 711 80834 C412 T F K G E V W C N D I R K L A
Rat Rattus norvegicus Q01992 710 80655 C411 P F K G E V W C I D V R K L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519255 686 77419 C387 P A K G E V W C E D V R K L A
Chicken Gallus gallus XP_417136 704 79533 S406 T Q R G E V W S E D V R K L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344847 700 79903 S401 P S V G E V W S E D V R K L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610183 699 80218 H396 L K P G E A W H N D I Y K L A
Honey Bee Apis mellifera XP_396237 696 80078 A398 V L S G E V W A N N V H K I V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182998 420 47731 A140 D A C M A V S A T V E V L N T
Poplar Tree Populus trichocarpa XP_002321840 726 81749 H425 M A P G E S W H P D V L K M S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35999 772 88164 S458 T D E G E T W S P D V R R L N
Red Bread Mold Neurospora crassa Q7SDD5 805 91077 H457 P M P G E T W H P D V R R L D
Conservation
Percent
Protein Identity: 100 N.A. 97.9 85.6 N.A. 82.8 83.4 N.A. 77 78.6 N.A. 71.3 N.A. 47.5 46 N.A. 29.1
Protein Similarity: 100 N.A. 98.8 89.4 N.A. 90 89.1 N.A. 85.5 88.5 N.A. 84.4 N.A. 65.7 66 N.A. 43
P-Site Identity: 100 N.A. 100 93.3 N.A. 66.6 80 N.A. 93.3 80 N.A. 86.6 N.A. 46.6 40 N.A. 13.3
P-Site Similarity: 100 N.A. 100 93.3 N.A. 73.3 80 N.A. 93.3 86.6 N.A. 93.3 N.A. 53.3 60 N.A. 20
Percent
Protein Identity: 34.5 N.A. N.A. N.A. 31.3 29.8
Protein Similarity: 53.8 N.A. N.A. N.A. 50.9 46
P-Site Identity: 46.6 N.A. N.A. N.A. 53.3 53.3
P-Site Similarity: 60 N.A. N.A. N.A. 66.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 43 0 0 8 8 0 15 0 0 0 0 0 0 65 % A
% Cys: 0 0 8 0 0 0 0 29 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 86 0 0 0 0 8 % D
% Glu: 0 0 8 0 93 0 0 0 43 0 8 0 0 0 0 % E
% Phe: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 22 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 15 0 0 8 0 % I
% Lys: 0 8 43 0 0 0 0 0 0 0 0 0 79 0 0 % K
% Leu: 8 8 0 0 0 0 0 0 0 0 0 8 8 79 0 % L
% Met: 8 8 0 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 22 8 0 0 0 8 8 % N
% Pro: 50 0 22 0 0 0 0 0 22 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 72 15 0 0 % R
% Ser: 0 8 8 0 0 8 8 36 0 0 0 0 0 0 8 % S
% Thr: 22 0 0 0 0 15 0 0 8 0 0 0 0 0 8 % T
% Val: 8 0 8 0 0 72 0 0 0 8 79 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 93 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _