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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDFI
All Species:
8.79
Human Site:
S146
Identified Species:
24.17
UniProt:
Q99750
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99750
NP_005577.1
246
25029
S146
Q
G
S
K
K
S
K
S
S
S
K
S
T
T
S
Chimpanzee
Pan troglodytes
XP_001174195
246
24967
S146
Q
G
S
K
K
S
K
S
S
S
K
S
T
T
S
Rhesus Macaque
Macaca mulatta
XP_001083151
185
18797
Q97
T
A
S
Q
I
P
L
Q
A
Q
E
D
C
C
V
Dog
Lupus familis
XP_851321
306
31586
S163
Q
G
S
K
K
S
K
S
S
T
K
S
T
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P70331
251
25994
G147
Q
A
G
R
K
S
R
G
S
A
R
S
A
S
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518156
486
50430
P387
P
P
T
P
T
S
L
P
A
H
G
G
R
K
R
Chicken
Gallus gallus
XP_418042
227
23771
E139
A
S
S
H
I
P
I
E
A
Q
E
D
C
C
V
Frog
Xenopus laevis
Q98SK0
246
26747
E151
D
G
S
K
K
S
K
E
S
S
A
Y
S
Q
K
Zebra Danio
Brachydanio rerio
XP_002661396
212
22460
P124
S
S
T
G
S
H
K
P
G
S
T
P
E
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
71.1
63.7
N.A.
47.8
N.A.
N.A.
30
54
41.8
39.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
71.9
67.3
N.A.
54.5
N.A.
N.A.
37.4
63.4
56.5
54
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
33.3
N.A.
N.A.
6.6
6.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
66.6
N.A.
N.A.
20
20
60
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
0
0
0
0
0
0
34
12
12
0
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
23
23
12
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
23
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
23
0
0
23
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
45
12
12
0
0
0
12
12
0
12
12
0
0
0
% G
% His:
0
0
0
12
0
12
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
23
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
45
56
0
56
0
0
0
34
0
0
12
12
% K
% Leu:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
12
0
23
0
23
0
0
0
12
0
0
0
% P
% Gln:
45
0
0
12
0
0
0
12
0
23
0
0
0
12
12
% Q
% Arg:
0
0
0
12
0
0
12
0
0
0
12
0
12
0
12
% R
% Ser:
12
23
67
0
12
67
0
34
56
45
0
45
12
12
34
% S
% Thr:
12
0
23
0
12
0
0
0
0
12
12
0
34
23
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _