KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDFI
All Species:
20.91
Human Site:
S138
Identified Species:
57.5
UniProt:
Q99750
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99750
NP_005577.1
246
25029
S138
Q
T
H
P
S
L
A
S
Q
G
S
K
K
S
K
Chimpanzee
Pan troglodytes
XP_001174195
246
24967
S138
Q
T
H
P
S
L
A
S
Q
G
S
K
K
S
K
Rhesus Macaque
Macaca mulatta
XP_001083151
185
18797
S89
K
S
K
S
S
T
K
S
T
A
S
Q
I
P
L
Dog
Lupus familis
XP_851321
306
31586
S155
Q
T
H
P
S
L
A
S
Q
G
S
K
K
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P70331
251
25994
S139
Q
T
H
P
S
L
G
S
Q
A
G
R
K
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518156
486
50430
K379
G
G
S
R
T
P
R
K
P
P
T
P
T
S
L
Chicken
Gallus gallus
XP_418042
227
23771
S131
K
S
K
G
S
S
K
S
A
S
S
H
I
P
I
Frog
Xenopus laevis
Q98SK0
246
26747
S143
Q
S
S
L
S
V
S
S
D
G
S
K
K
S
K
Zebra Danio
Brachydanio rerio
XP_002661396
212
22460
S116
D
S
S
R
R
S
K
S
S
S
T
G
S
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
71.1
63.7
N.A.
47.8
N.A.
N.A.
30
54
41.8
39.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
71.9
67.3
N.A.
54.5
N.A.
N.A.
37.4
63.4
56.5
54
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
100
N.A.
66.6
N.A.
N.A.
6.6
20
60
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
80
N.A.
N.A.
20
33.3
80
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
34
0
12
23
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
12
0
0
12
0
0
45
12
12
0
0
0
% G
% His:
0
0
45
0
0
0
0
0
0
0
0
12
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
12
% I
% Lys:
23
0
23
0
0
0
34
12
0
0
0
45
56
0
56
% K
% Leu:
0
0
0
12
0
45
0
0
0
0
0
0
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
45
0
12
0
0
12
12
0
12
0
23
0
% P
% Gln:
56
0
0
0
0
0
0
0
45
0
0
12
0
0
0
% Q
% Arg:
0
0
0
23
12
0
12
0
0
0
0
12
0
0
12
% R
% Ser:
0
45
34
12
78
23
12
89
12
23
67
0
12
67
0
% S
% Thr:
0
45
0
0
12
12
0
0
12
0
23
0
12
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _