Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MDFI All Species: 10.3
Human Site: S104 Identified Species: 28.33
UniProt: Q99750 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99750 NP_005577.1 246 25029 S104 T P L L P N D S G H P S E L G
Chimpanzee Pan troglodytes XP_001174195 246 24967 S104 T P L L P N G S G H P S E L G
Rhesus Macaque Macaca mulatta XP_001083151 185 18797 A59 T R R A G N G A L G G P K A H
Dog Lupus familis XP_851321 306 31586 S121 T P L V A N G S G H P S E L S
Cat Felis silvestris
Mouse Mus musculus P70331 251 25994 S103 T P L L P N G S S H D H L S E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518156 486 50430 L349 G P P G C I P L L H N G T G G
Chicken Gallus gallus XP_418042 227 23771 L101 G N G V F R P L P S S Q K P H
Frog Xenopus laevis Q98SK0 246 26747 N111 S N I N G I H N G V K H V P A
Zebra Danio Brachydanio rerio XP_002661396 212 22460 R86 S I H T S E P R K L P S P V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 71.1 63.7 N.A. 47.8 N.A. N.A. 30 54 41.8 39.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 71.9 67.3 N.A. 54.5 N.A. N.A. 37.4 63.4 56.5 54 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 13.3 73.3 N.A. 53.3 N.A. N.A. 20 0 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 26.6 80 N.A. 53.3 N.A. N.A. 20 13.3 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 12 0 0 12 0 0 0 0 0 12 12 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 12 0 0 0 0 % D
% Glu: 0 0 0 0 0 12 0 0 0 0 0 0 34 0 12 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 23 0 12 12 23 0 45 0 45 12 12 12 0 12 34 % G
% His: 0 0 12 0 0 0 12 0 0 56 0 23 0 0 23 % H
% Ile: 0 12 12 0 0 23 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 12 0 12 0 23 0 0 % K
% Leu: 0 0 45 34 0 0 0 23 23 12 0 0 12 34 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 23 0 12 0 56 0 12 0 0 12 0 0 0 0 % N
% Pro: 0 56 12 0 34 0 34 0 12 0 45 12 12 23 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Q
% Arg: 0 12 12 0 0 12 0 12 0 0 0 0 0 0 0 % R
% Ser: 23 0 0 0 12 0 0 45 12 12 12 45 0 12 23 % S
% Thr: 56 0 0 12 0 0 0 0 0 0 0 0 12 0 0 % T
% Val: 0 0 0 23 0 0 0 0 0 12 0 0 12 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _