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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS2
All Species:
33.94
Human Site:
Y353
Identified Species:
74.67
UniProt:
Q99743
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99743
NP_002509.2
824
91761
Y353
C
T
H
S
V
V
S
Y
A
D
V
R
V
E
R
Chimpanzee
Pan troglodytes
XP_515656
1383
151405
Y912
C
T
H
S
V
V
S
Y
A
D
V
R
V
E
R
Rhesus Macaque
Macaca mulatta
XP_001105763
824
91854
Y353
C
T
H
S
V
V
S
Y
A
D
V
R
V
E
R
Dog
Lupus familis
XP_531781
878
97540
Y413
C
T
H
S
V
V
S
Y
A
D
V
R
V
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P97460
816
90897
Y353
C
T
H
S
V
V
S
Y
A
D
V
R
V
E
R
Rat
Rattus norvegicus
Q9WVS9
862
96985
Y378
C
T
H
T
V
V
S
Y
A
E
V
R
A
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512993
773
87772
G322
Y
Y
R
F
L
T
K
G
Q
Q
W
I
W
L
Q
Chicken
Gallus gallus
Q5ZQU2
815
91159
Y353
C
T
H
M
V
V
S
Y
A
D
V
R
V
E
R
Frog
Xenopus laevis
NP_001083854
825
93251
Y369
C
T
H
T
V
V
S
Y
A
E
V
G
A
E
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61735
1027
116123
Y369
C
T
H
K
V
V
S
Y
A
E
V
L
K
D
S
Honey Bee
Apis mellifera
XP_394233
708
81000
F257
R
H
S
L
E
W
K
F
L
F
L
D
H
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.5
99.2
85
N.A.
87.5
48.7
N.A.
50
73.6
49.7
N.A.
N.A.
30.4
36.7
N.A.
N.A.
Protein Similarity:
100
59.5
99.3
88.5
N.A.
91.1
63.4
N.A.
64.1
81.8
64.9
N.A.
N.A.
45.6
52.6
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
0
93.3
73.3
N.A.
N.A.
60
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
13.3
93.3
86.6
N.A.
N.A.
73.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
82
0
0
0
19
0
10
% A
% Cys:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
55
0
10
0
10
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
28
0
0
0
73
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% G
% His:
0
10
82
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
19
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
10
0
10
10
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
64
0
10
73
% R
% Ser:
0
0
10
46
0
0
82
0
0
0
0
0
0
0
10
% S
% Thr:
0
82
0
19
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
82
82
0
0
0
0
82
0
55
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% W
% Tyr:
10
10
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _