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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPAS2 All Species: 11.21
Human Site: S164 Identified Species: 24.67
UniProt: Q99743 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99743 NP_002509.2 824 91761 S164 P E Y L K S D S D L E F Y C H
Chimpanzee Pan troglodytes XP_515656 1383 151405 S723 P E Y L K S D S D L E F Y C H
Rhesus Macaque Macaca mulatta XP_001105763 824 91854 S164 P E Y L K S D S D L E F Y C H
Dog Lupus familis XP_531781 878 97540 N224 P E Y L K S D N D L E F Y C H
Cat Felis silvestris
Mouse Mus musculus P97460 816 90897 N164 P E F L K S D N D L E F Y C H
Rat Rattus norvegicus Q9WVS9 862 96985 N189 P E D L K S K N Q L E F C C H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512993 773 87772 S148 S E V Y K L L S P H V L M T D
Chicken Gallus gallus Q5ZQU2 815 91159 N164 S D C L K T D N E L E F Y C H
Frog Xenopus laevis NP_001083854 825 93251 N180 S E Y L K T K N E L E F C C H
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61735 1027 116123 N169 Q T D I S S S N Q I T F Y T H
Honey Bee Apis mellifera XP_394233 708 81000 S83 D W K P S F L S N E E F T H L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.5 99.2 85 N.A. 87.5 48.7 N.A. 50 73.6 49.7 N.A. N.A. 30.4 36.7 N.A. N.A.
Protein Similarity: 100 59.5 99.3 88.5 N.A. 91.1 63.4 N.A. 64.1 81.8 64.9 N.A. N.A. 45.6 52.6 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 86.6 66.6 N.A. 20 60 60 N.A. N.A. 26.6 20 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 73.3 N.A. 20 86.6 80 N.A. N.A. 46.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 19 73 0 % C
% Asp: 10 10 19 0 0 0 55 0 46 0 0 0 0 0 10 % D
% Glu: 0 73 0 0 0 0 0 0 19 10 82 0 0 0 0 % E
% Phe: 0 0 10 0 0 10 0 0 0 0 0 91 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 82 % H
% Ile: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 10 0 82 0 19 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 73 0 10 19 0 0 73 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 55 10 0 0 0 0 0 0 % N
% Pro: 55 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 0 0 0 19 64 10 46 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 19 0 0 0 0 10 0 10 19 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 46 10 0 0 0 0 0 0 0 0 64 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _