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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS1
All Species:
1.21
Human Site:
S246
Identified Species:
3.33
UniProt:
Q99742
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99742
NP_002508.2
590
62702
S246
S
S
L
V
Q
E
R
S
F
F
V
R
M
K
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112801
591
62798
R246
P
S
S
L
V
Q
E
R
S
F
F
V
R
M
K
Dog
Lupus familis
XP_541539
594
63373
E247
P
P
F
S
R
V
Q
E
R
S
F
F
I
R
M
Cat
Felis silvestris
Mouse
Mus musculus
P97459
594
63718
R246
P
A
F
R
A
Q
E
R
S
F
F
V
R
M
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
T245
S
L
L
T
T
D
N
T
L
E
R
S
F
F
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
P351
G
T
H
G
T
N
N
P
D
V
A
A
S
M
T
Honey Bee
Apis mellifera
XP_391937
963
103825
A313
S
S
V
M
S
L
S
A
N
N
L
Y
K
G
Y
Nematode Worm
Caenorhab. elegans
P90953
322
36743
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
R268
N
M
T
A
S
S
D
R
I
E
R
S
F
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
89.7
N.A.
86.6
N.A.
N.A.
42.7
N.A.
N.A.
N.A.
N.A.
31
31.3
21
32.1
Protein Similarity:
100
N.A.
98.8
93
N.A.
90.4
N.A.
N.A.
57.9
N.A.
N.A.
N.A.
N.A.
40.5
41.5
32.5
43.1
P-Site Identity:
100
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
13.3
0
0
P-Site Similarity:
100
N.A.
26.6
26.6
N.A.
20
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
13.3
40
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
12
0
0
12
0
0
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
12
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
23
12
0
23
0
0
0
0
0
% E
% Phe:
0
0
23
0
0
0
0
0
12
34
34
12
23
12
0
% F
% Gly:
12
0
0
12
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
23
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
23
% K
% Leu:
0
12
23
12
0
12
0
0
12
0
12
0
0
12
0
% L
% Met:
0
12
0
12
0
0
0
0
0
0
0
0
12
34
12
% M
% Asn:
12
0
0
0
0
12
23
0
12
12
0
0
0
0
0
% N
% Pro:
34
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
23
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
12
0
12
34
12
0
23
12
23
12
0
% R
% Ser:
34
34
12
12
23
12
12
12
23
12
0
23
12
0
12
% S
% Thr:
0
12
12
12
23
0
0
12
0
0
0
0
0
0
12
% T
% Val:
0
0
12
12
12
12
0
0
0
12
12
23
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _