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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGMAR1
All Species:
24.5
Human Site:
Y217
Identified Species:
49
UniProt:
Q99720
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99720
NP_005857.1
223
25128
Y217
L
R
L
E
L
T
T
Y
L
F
G
Q
D
P
_
Chimpanzee
Pan troglodytes
XP_001163744
215
24311
Y209
L
R
L
E
L
T
T
Y
L
F
G
Q
D
P
_
Rhesus Macaque
Macaca mulatta
XP_001095863
203
22785
Y197
L
R
L
E
L
T
T
Y
L
F
G
Q
D
P
_
Dog
Lupus familis
XP_852544
223
25083
Y217
L
R
L
E
F
T
T
Y
L
F
G
Q
D
P
_
Cat
Felis silvestris
Mouse
Mus musculus
O55242
223
25231
Y217
L
R
L
E
L
T
T
Y
L
F
G
Q
D
S
_
Rat
Rattus norvegicus
Q9R0C9
223
25251
Y217
L
R
L
E
L
T
T
Y
L
F
G
Q
D
P
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL84
222
24584
F216
L
L
L
E
A
S
A
F
F
S
T
L
G
C
_
Frog
Xenopus laevis
Q6DCU6
221
24677
H214
L
L
L
E
A
S
T
H
L
S
Q
L
G
F
F
Zebra Danio
Brachydanio rerio
Q7ZWG9
222
24922
F215
M
I
L
E
A
S
T
F
L
T
E
S
G
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783805
210
23776
T184
V
S
D
T
I
F
S
T
Q
D
F
Y
T
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32352
222
24877
T195
F
L
D
T
F
S
S
T
L
D
L
Y
T
L
Y
Red Bread Mold
Neurospora crassa
Q92254
256
28227
L236
S
T
L
D
F
P
T
L
W
R
T
S
V
I
T
Conservation
Percent
Protein Identity:
100
94.1
91
97.7
N.A.
90.1
93.7
N.A.
N.A.
65.9
67.7
63.6
N.A.
N.A.
N.A.
N.A.
52.9
Protein Similarity:
100
95
91
98.6
N.A.
93.7
95.9
N.A.
N.A.
79.3
84.7
79.3
N.A.
N.A.
N.A.
N.A.
69.9
P-Site Identity:
100
100
100
92.8
N.A.
92.8
100
N.A.
N.A.
21.4
33.3
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
92.8
N.A.
92.8
100
N.A.
N.A.
35.7
46.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
30.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
46.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
17
9
0
0
0
0
0
17
0
0
50
0
0
% D
% Glu:
0
0
0
75
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
9
0
0
0
25
9
0
17
9
50
9
0
0
9
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
50
0
25
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
67
25
84
0
42
0
0
9
75
0
9
17
0
17
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
42
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
9
50
0
0
0
% Q
% Arg:
0
50
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
9
9
0
0
0
34
17
0
0
17
0
17
0
9
0
% S
% Thr:
0
9
0
17
0
50
75
17
0
9
17
0
17
0
9
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
17
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% _