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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B10
All Species:
22.12
Human Site:
T100
Identified Species:
44.24
UniProt:
Q99714
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99714
NP_001032900.1
261
26923
T100
G
I
A
V
A
S
K
T
Y
N
L
K
K
G
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087982
261
27083
T100
G
I
A
V
A
I
K
T
Y
N
L
K
K
S
Q
Dog
Lupus familis
XP_538051
261
27137
T100
G
I
A
V
A
I
K
T
Y
N
L
K
K
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
O08756
261
27400
T100
G
I
A
V
A
I
K
T
Y
H
Q
K
K
N
K
Rat
Rattus norvegicus
O70351
261
27227
T100
G
I
A
V
A
I
K
T
Y
H
E
K
K
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512537
205
21655
E79
V
I
R
L
C
A
G
E
M
G
K
N
D
P
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NUE2
236
25189
I85
Y
L
V
N
S
A
G
I
S
R
D
A
L
L
L
Zebra Danio
Brachydanio rerio
Q6P0H7
237
24860
I87
F
L
V
N
A
A
G
I
N
R
D
A
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18404
255
26886
T94
G
T
A
T
A
V
K
T
F
N
F
N
K
N
V
Honey Bee
Apis mellifera
XP_001120471
254
27081
V93
G
I
A
V
A
H
K
V
Y
N
F
N
K
D
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780014
260
27301
T99
G
I
G
V
A
V
K
T
Y
N
F
N
K
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P33207
319
33530
T168
N
A
G
I
T
R
D
T
L
L
I
R
M
K
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
91.9
N.A.
86.2
87.7
N.A.
63.2
N.A.
29.5
30.6
N.A.
67.4
60.9
N.A.
68.2
Protein Similarity:
100
N.A.
97.6
95
N.A.
93.4
94.2
N.A.
72.8
N.A.
47.8
49.8
N.A.
78.5
71.6
N.A.
79.3
P-Site Identity:
100
N.A.
86.6
86.6
N.A.
66.6
73.3
N.A.
6.6
N.A.
0
6.6
N.A.
46.6
60
N.A.
60
P-Site Similarity:
100
N.A.
86.6
86.6
N.A.
80
80
N.A.
20
N.A.
20
20
N.A.
53.3
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
59
0
75
25
0
0
0
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
17
0
9
17
9
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
25
0
0
0
0
% F
% Gly:
67
0
17
0
0
0
25
0
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
67
0
9
0
34
0
17
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
67
0
0
0
9
42
67
9
9
% K
% Leu:
0
17
0
9
0
0
0
0
9
9
25
0
17
17
17
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% M
% Asn:
9
0
0
17
0
0
0
0
9
50
0
34
0
34
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
42
% Q
% Arg:
0
0
9
0
0
9
0
0
0
17
0
9
0
0
9
% R
% Ser:
0
0
0
0
9
9
0
0
9
0
0
0
0
9
0
% S
% Thr:
0
9
0
9
9
0
0
67
0
0
0
0
0
0
0
% T
% Val:
9
0
17
59
0
17
0
9
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _