KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B10
All Species:
16.67
Human Site:
S45
Identified Species:
33.33
UniProt:
Q99714
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99714
NP_001032900.1
261
26923
S45
V
L
L
D
L
P
N
S
G
G
E
A
Q
A
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087982
261
27083
S45
V
L
L
D
L
P
N
S
G
G
E
A
Q
A
K
Dog
Lupus familis
XP_538051
261
27137
S45
V
L
L
D
L
P
N
S
D
G
E
V
Q
A
K
Cat
Felis silvestris
Mouse
Mus musculus
O08756
261
27400
S45
V
L
L
D
V
P
D
S
E
G
E
S
Q
A
K
Rat
Rattus norvegicus
O70351
261
27227
S45
V
L
L
D
V
P
N
S
E
G
E
T
E
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512537
205
21655
V40
V
N
C
A
G
I
A
V
A
I
K
T
Y
N
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NUE2
236
25189
E45
V
A
Q
A
A
V
T
E
I
G
A
H
L
A
L
Zebra Danio
Brachydanio rerio
Q6P0H7
237
24860
G48
S
T
A
Q
S
L
P
G
E
N
H
L
G
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18404
255
26886
A45
S
S
K
G
N
E
V
A
K
E
L
G
D
K
V
Honey Bee
Apis mellifera
XP_001120471
254
27081
A51
A
N
E
L
G
E
S
A
V
F
T
P
V
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780014
260
27301
P45
I
V
D
L
P
N
S
P
G
E
E
V
A
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P33207
319
33530
A111
L
V
N
Y
A
R
S
A
K
E
A
E
E
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
91.9
N.A.
86.2
87.7
N.A.
63.2
N.A.
29.5
30.6
N.A.
67.4
60.9
N.A.
68.2
Protein Similarity:
100
N.A.
97.6
95
N.A.
93.4
94.2
N.A.
72.8
N.A.
47.8
49.8
N.A.
78.5
71.6
N.A.
79.3
P-Site Identity:
100
N.A.
100
86.6
N.A.
73.3
73.3
N.A.
6.6
N.A.
20
0
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
86.6
N.A.
13.3
N.A.
20
0
N.A.
6.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
17
17
0
9
25
9
0
17
17
9
50
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
42
0
0
9
0
9
0
0
0
9
9
0
% D
% Glu:
0
0
9
0
0
17
0
9
25
25
50
9
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
9
17
0
0
9
25
50
0
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% H
% Ile:
9
0
0
0
0
9
0
0
9
9
0
0
0
0
9
% I
% Lys:
0
0
9
0
0
0
0
0
17
0
9
0
0
17
42
% K
% Leu:
9
42
42
17
25
9
0
0
0
0
9
9
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
9
0
9
9
34
0
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
9
42
9
9
0
0
0
9
0
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
0
0
34
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
9
0
0
9
0
25
42
0
0
0
9
0
0
17
% S
% Thr:
0
9
0
0
0
0
9
0
0
0
9
17
0
0
0
% T
% Val:
59
17
0
0
17
9
9
9
9
0
0
17
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _