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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K5
All Species:
15.45
Human Site:
S1311
Identified Species:
34
UniProt:
Q99683
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99683
NP_005914.1
1374
154537
S1311
S
G
T
N
T
E
D
S
E
L
T
D
W
L
R
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
S1312
S
G
T
N
T
E
D
S
E
L
T
D
W
L
R
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
Q1224
P
A
T
L
S
T
D
Q
G
L
V
Q
W
L
Q
Dog
Lupus familis
XP_533420
1645
181128
S1582
P
G
T
N
T
E
E
S
E
L
T
E
W
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O35099
1380
154441
S1318
P
G
T
T
T
E
D
S
E
L
P
G
W
L
R
Rat
Rattus norvegicus
XP_001073260
1338
150427
S1275
P
G
T
A
I
E
D
S
E
L
T
G
W
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511920
1243
141469
P1180
T
G
L
N
A
E
D
P
E
L
R
P
W
L
R
Chicken
Gallus gallus
XP_419725
1260
143069
P1197
T
G
T
G
T
E
D
P
D
L
I
N
W
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
L1301
S
L
D
G
D
G
D
L
Q
L
L
E
W
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477089
1363
155478
E1241
F
G
L
H
E
V
D
E
Q
L
E
Q
W
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
E1223
A
G
V
E
A
K
Q
E
E
L
S
S
W
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
44.9
68
N.A.
94.1
92.7
N.A.
84.4
80.4
N.A.
71.7
N.A.
40.6
N.A.
N.A.
44.6
Protein Similarity:
100
99.4
61.3
73.1
N.A.
95.8
94.4
N.A.
87.8
87
N.A.
84.1
N.A.
58.2
N.A.
N.A.
60.7
P-Site Identity:
100
100
33.3
80
N.A.
73.3
73.3
N.A.
60
53.3
N.A.
33.3
N.A.
33.3
N.A.
N.A.
33.3
P-Site Similarity:
100
100
46.6
93.3
N.A.
73.3
73.3
N.A.
66.6
73.3
N.A.
53.3
N.A.
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
19
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
82
0
10
0
0
19
0
0
0
% D
% Glu:
0
0
0
10
10
64
10
19
64
0
10
19
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
82
0
19
0
10
0
0
10
0
0
19
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
19
10
0
0
0
10
0
100
10
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
37
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
37
0
0
0
0
0
0
19
0
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
10
19
0
0
19
0
0
19
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
55
% R
% Ser:
28
0
0
0
10
0
0
46
0
0
10
10
0
0
10
% S
% Thr:
19
0
64
10
46
10
0
0
0
0
37
0
0
0
10
% T
% Val:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _