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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR21
All Species:
13.94
Human Site:
S233
Identified Species:
27.88
UniProt:
Q99679
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99679
NP_005285.1
349
39515
S233
S
E
R
Q
A
R
F
S
S
Q
S
G
E
T
G
Chimpanzee
Pan troglodytes
Q5W8W0
345
38508
I231
A
R
R
Q
A
K
K
I
E
N
T
G
S
K
T
Rhesus Macaque
Macaca mulatta
P47899
480
51591
E262
V
K
K
I
D
S
C
E
R
R
F
L
G
G
P
Dog
Lupus familis
XP_851557
352
39896
S233
S
E
R
Q
A
R
F
S
S
Q
S
G
E
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX79
349
39491
S233
S
E
R
Q
A
R
F
S
S
Q
N
G
E
T
G
Rat
Rattus norvegicus
P10608
418
46873
E237
L
Q
K
I
D
K
S
E
G
R
F
H
A
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511875
349
39294
S233
N
E
R
R
A
R
F
S
G
Q
S
G
E
A
G
Chicken
Gallus gallus
O13076
340
37753
L226
M
G
N
S
R
T
T
L
Q
K
E
V
H
A
A
Frog
Xenopus laevis
O42574
385
43291
C239
Q
M
K
K
I
D
K
C
E
G
R
F
S
H
S
Zebra Danio
Brachydanio rerio
NP_001128606
405
45165
A237
C
E
I
P
E
G
S
A
R
S
Y
S
R
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
G280
P
H
L
S
E
L
T
G
G
S
V
I
E
N
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186543
430
48225
S288
R
S
E
M
M
F
K
S
A
S
Q
R
E
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.5
21
94.5
N.A.
91.1
23.2
N.A.
85.3
27.2
26.4
25.4
N.A.
20.9
N.A.
N.A.
29.7
Protein Similarity:
100
42.9
35.6
96.8
N.A.
95.9
43
N.A.
91.6
44.4
43.3
44.4
N.A.
36.9
N.A.
N.A.
44.8
P-Site Identity:
100
26.6
0
100
N.A.
93.3
0
N.A.
73.3
0
0
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
46.6
20
100
N.A.
100
26.6
N.A.
86.6
6.6
13.3
13.3
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
42
0
0
9
9
0
0
0
9
17
9
% A
% Cys:
9
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
42
9
0
17
0
0
17
17
0
9
0
50
0
0
% E
% Phe:
0
0
0
0
0
9
34
0
0
0
17
9
0
0
0
% F
% Gly:
0
9
0
0
0
9
0
9
25
9
0
42
9
17
34
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
9
9
9
0
% H
% Ile:
0
0
9
17
9
0
0
9
0
0
0
9
0
0
9
% I
% Lys:
0
9
25
9
0
17
25
0
0
9
0
0
0
9
0
% K
% Leu:
9
0
9
0
0
9
0
9
0
0
0
9
0
0
0
% L
% Met:
9
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
9
9
0
0
9
9
% N
% Pro:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
9
9
0
34
0
0
0
0
9
34
9
0
0
9
0
% Q
% Arg:
9
9
42
9
9
34
0
0
17
17
9
9
9
9
0
% R
% Ser:
25
9
0
17
0
9
17
42
25
25
25
9
17
0
9
% S
% Thr:
0
0
0
0
0
9
17
0
0
0
9
0
0
25
25
% T
% Val:
9
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _