KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS8
All Species:
42.42
Human Site:
Y90
Identified Species:
62.22
UniProt:
Q99627
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99627
NP_006701.1
209
23226
Y90
Q
R
D
F
P
G
I
Y
T
T
I
N
A
H
Q
Chimpanzee
Pan troglodytes
XP_001135161
209
23311
Y90
Q
R
D
F
P
G
I
Y
T
T
I
N
A
H
Q
Rhesus Macaque
Macaca mulatta
XP_001090380
647
71562
Y528
Q
R
D
F
P
G
I
Y
T
T
I
N
A
H
Q
Dog
Lupus familis
XP_534612
209
23195
Y90
Q
R
D
F
P
G
I
Y
T
T
I
N
A
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV7
209
23237
Y90
Q
R
D
F
P
G
I
Y
T
T
I
N
A
H
Q
Rat
Rattus norvegicus
Q6P4Z9
209
23217
Y90
Q
R
D
F
P
G
I
Y
T
T
I
N
A
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507694
204
22617
Y87
Q
R
D
F
P
G
I
Y
T
T
I
S
A
H
Q
Chicken
Gallus gallus
NP_001041472
207
22961
Y90
Q
R
D
F
P
G
I
Y
T
T
I
S
A
H
Q
Frog
Xenopus laevis
Q6GQA6
195
21737
Y92
Q
R
D
F
P
G
I
Y
T
S
I
S
A
Y
Q
Zebra Danio
Brachydanio rerio
Q7ZUZ0
191
21527
Y88
Q
R
D
F
P
G
I
Y
S
A
I
A
A
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTH8
182
21413
I83
Y
A
D
F
F
K
H
I
K
Y
E
W
S
E
R
Honey Bee
Apis mellifera
XP_391971
187
21201
H83
Q
R
D
W
P
A
V
H
V
A
L
N
A
E
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203845
168
18975
L69
S
S
K
L
Y
S
A
L
N
R
E
W
S
D
V
Poplar Tree
Populus trichocarpa
XP_002298193
199
22672
H97
T
R
D
Y
A
A
V
H
E
A
I
R
A
F
D
Maize
Zea mays
NP_001141592
196
22092
N94
K
R
D
Y
A
G
V
N
T
A
A
Q
G
F
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43255
197
22528
Y95
T
H
D
Y
A
G
V
Y
E
A
I
R
G
Y
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
31.6
98
N.A.
95.2
95.6
N.A.
84.2
88
74.1
67.9
N.A.
27.2
46.8
N.A.
43.5
Protein Similarity:
100
96.6
32.2
99.5
N.A.
98
98
N.A.
91.8
93.7
85.1
77.9
N.A.
46.8
63.1
N.A.
63.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
80
73.3
N.A.
13.3
40
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
26.6
66.6
N.A.
6.6
Percent
Protein Identity:
32.5
32.5
N.A.
33.4
N.A.
N.A.
Protein Similarity:
55.5
52.1
N.A.
53.1
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
46.6
53.3
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
19
13
7
0
0
32
7
7
75
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
94
0
0
0
0
0
0
0
0
0
0
7
13
% D
% Glu:
0
0
0
0
0
0
0
0
13
0
13
0
0
13
7
% E
% Phe:
0
0
0
69
7
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
0
75
0
0
0
0
0
0
13
0
0
% G
% His:
0
7
0
0
0
0
7
13
0
0
0
0
0
50
0
% H
% Ile:
0
0
0
0
0
0
63
7
0
0
75
0
0
0
0
% I
% Lys:
7
0
7
0
0
7
0
0
7
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
7
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
0
44
0
0
0
% N
% Pro:
0
0
0
0
69
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
69
0
0
0
0
0
0
0
0
0
0
7
0
0
63
% Q
% Arg:
0
82
0
0
0
0
0
0
0
7
0
13
0
0
7
% R
% Ser:
7
7
0
0
0
7
0
0
7
7
0
19
13
0
0
% S
% Thr:
13
0
0
0
0
0
0
0
63
50
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
25
0
7
0
0
0
0
0
7
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
13
0
0
7
% W
% Tyr:
7
0
0
19
7
0
0
69
0
7
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _