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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS8
All Species:
28.18
Human Site:
T158
Identified Species:
41.33
UniProt:
Q99627
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99627
NP_006701.1
209
23226
T158
Q
G
W
Q
A
D
S
T
T
R
M
V
L
P
R
Chimpanzee
Pan troglodytes
XP_001135161
209
23311
T158
Q
G
W
Q
V
D
S
T
T
R
M
V
L
P
R
Rhesus Macaque
Macaca mulatta
XP_001090380
647
71562
T596
Q
G
W
Q
A
D
S
T
T
R
M
V
L
P
R
Dog
Lupus familis
XP_534612
209
23195
T158
Q
G
W
Q
A
D
S
T
T
R
M
V
M
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV7
209
23237
T158
Q
G
W
Q
A
D
S
T
T
R
M
V
L
P
R
Rat
Rattus norvegicus
Q6P4Z9
209
23217
T158
Q
G
W
Q
A
D
S
T
T
R
M
V
L
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507694
204
22617
A141
V
G
L
P
V
E
D
A
V
K
G
V
L
D
Q
Chicken
Gallus gallus
NP_001041472
207
22961
A144
V
G
L
P
V
E
E
A
V
K
G
V
L
E
Q
Frog
Xenopus laevis
Q6GQA6
195
21737
A146
V
G
L
P
V
E
E
A
V
K
G
V
L
E
Q
Zebra Danio
Brachydanio rerio
Q7ZUZ0
191
21527
A142
V
G
Y
S
V
E
E
A
V
K
G
V
V
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTH8
182
21413
A136
S
E
D
E
L
K
H
A
C
A
A
L
N
W
T
Honey Bee
Apis mellifera
XP_391971
187
21201
A136
T
G
L
T
L
E
E
A
R
R
V
A
I
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203845
168
18975
A122
S
K
E
Q
A
I
N
A
V
Q
E
E
G
W
S
Poplar Tree
Populus trichocarpa
XP_002298193
199
22672
T152
G
M
N
E
D
D
A
T
S
Y
V
L
Q
Q
G
Maize
Zea mays
NP_001141592
196
22092
T149
G
M
S
E
E
D
A
T
N
Y
A
V
Q
N
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43255
197
22528
T150
G
M
T
E
D
D
A
T
T
Y
V
V
E
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
31.6
98
N.A.
95.2
95.6
N.A.
84.2
88
74.1
67.9
N.A.
27.2
46.8
N.A.
43.5
Protein Similarity:
100
96.6
32.2
99.5
N.A.
98
98
N.A.
91.8
93.7
85.1
77.9
N.A.
46.8
63.1
N.A.
63.1
P-Site Identity:
100
93.3
100
86.6
N.A.
100
100
N.A.
20
20
20
13.3
N.A.
0
20
N.A.
13.3
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
40
40
40
40
N.A.
13.3
40
N.A.
26.6
Percent
Protein Identity:
32.5
32.5
N.A.
33.4
N.A.
N.A.
Protein Similarity:
55.5
52.1
N.A.
53.1
N.A.
N.A.
P-Site Identity:
13.3
20
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
46.6
33.3
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
38
0
19
44
0
7
13
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
13
57
7
0
0
0
0
0
0
7
0
% D
% Glu:
0
7
7
25
7
32
25
0
0
0
7
7
7
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
69
0
0
0
0
0
0
0
0
25
0
7
0
19
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
7
0
0
0
7
0
0
0
25
0
0
0
0
7
% K
% Leu:
0
0
25
0
13
0
0
0
0
0
0
13
50
0
0
% L
% Met:
0
19
0
0
0
0
0
0
0
0
38
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
7
0
7
0
0
0
7
13
0
% N
% Pro:
0
0
0
19
0
0
0
0
0
0
0
0
0
38
0
% P
% Gln:
38
0
0
44
0
0
0
0
0
7
0
0
13
7
19
% Q
% Arg:
0
0
0
0
0
0
0
0
7
44
0
0
0
0
38
% R
% Ser:
13
0
7
7
0
0
38
0
7
0
0
0
0
7
7
% S
% Thr:
7
0
7
7
0
0
0
57
44
0
0
0
0
0
7
% T
% Val:
25
0
0
0
32
0
0
0
32
0
19
75
7
0
0
% V
% Trp:
0
0
38
0
0
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _