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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS8
All Species:
30.91
Human Site:
S69
Identified Species:
45.33
UniProt:
Q99627
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99627
NP_006701.1
209
23226
S69
P
A
I
K
S
A
N
S
E
L
G
G
I
W
S
Chimpanzee
Pan troglodytes
XP_001135161
209
23311
S69
P
A
T
K
S
A
N
S
E
L
G
G
I
W
S
Rhesus Macaque
Macaca mulatta
XP_001090380
647
71562
S507
P
A
I
K
S
A
N
S
E
L
G
G
I
W
S
Dog
Lupus familis
XP_534612
209
23195
S69
P
A
I
K
S
A
N
S
E
L
G
G
I
W
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV7
209
23237
S69
P
A
I
K
S
A
N
S
E
L
G
G
I
W
S
Rat
Rattus norvegicus
Q6P4Z9
209
23217
S69
P
A
I
K
S
A
N
S
E
L
G
G
I
W
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507694
204
22617
S66
P
A
I
K
S
A
N
S
E
L
G
G
I
W
S
Chicken
Gallus gallus
NP_001041472
207
22961
A69
P
A
I
K
S
A
N
A
E
L
G
A
V
W
S
Frog
Xenopus laevis
Q6GQA6
195
21737
S71
S
A
I
K
S
S
H
S
E
L
G
G
I
W
E
Zebra Danio
Brachydanio rerio
Q7ZUZ0
191
21527
P67
Q
A
I
K
T
A
N
P
E
M
A
A
I
W
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTH8
182
21413
I62
L
R
D
D
K
E
L
I
Q
L
N
L
L
N
I
Honey Bee
Apis mellifera
XP_391971
187
21201
A62
T
D
L
K
S
G
N
A
E
L
G
Q
I
W
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203845
168
18975
I48
A
D
P
E
L
G
Y
I
W
E
I
G
Q
N
M
Poplar Tree
Populus trichocarpa
XP_002298193
199
22672
P76
A
A
V
K
E
R
Q
P
E
V
V
A
A
W
G
Maize
Zea mays
NP_001141592
196
22092
P73
Q
E
V
K
D
T
R
P
E
L
A
A
V
W
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43255
197
22528
P74
T
A
I
K
E
R
K
P
E
V
V
A
A
W
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
31.6
98
N.A.
95.2
95.6
N.A.
84.2
88
74.1
67.9
N.A.
27.2
46.8
N.A.
43.5
Protein Similarity:
100
96.6
32.2
99.5
N.A.
98
98
N.A.
91.8
93.7
85.1
77.9
N.A.
46.8
63.1
N.A.
63.1
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
100
80
73.3
53.3
N.A.
6.6
53.3
N.A.
6.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
100
93.3
86.6
73.3
N.A.
20
66.6
N.A.
13.3
Percent
Protein Identity:
32.5
32.5
N.A.
33.4
N.A.
N.A.
Protein Similarity:
55.5
52.1
N.A.
53.1
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
40
40
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
75
0
0
0
57
0
13
0
0
13
32
13
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
7
7
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
7
13
7
0
0
88
7
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
0
0
0
0
63
57
0
0
13
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
63
0
0
0
0
13
0
0
7
0
63
0
7
% I
% Lys:
0
0
0
88
7
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
7
0
7
0
7
0
0
75
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
63
0
0
0
7
0
0
13
0
% N
% Pro:
50
0
7
0
0
0
0
25
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
7
0
7
0
0
7
7
0
0
% Q
% Arg:
0
7
0
0
0
13
7
0
0
0
0
0
0
0
7
% R
% Ser:
7
0
0
0
63
7
0
50
0
0
0
0
0
0
50
% S
% Thr:
13
0
7
0
7
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
13
0
0
0
0
0
0
13
13
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
88
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _