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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS8
All Species:
27.88
Human Site:
S175
Identified Species:
40.89
UniProt:
Q99627
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99627
NP_006701.1
209
23226
S175
V
A
G
A
L
D
V
S
F
N
K
F
I
P
L
Chimpanzee
Pan troglodytes
XP_001135161
209
23311
S175
V
A
G
A
L
D
V
S
F
N
K
F
I
P
L
Rhesus Macaque
Macaca mulatta
XP_001090380
647
71562
S613
V
A
G
A
L
D
V
S
F
N
K
F
I
P
L
Dog
Lupus familis
XP_534612
209
23195
S175
V
A
G
A
L
D
V
S
F
N
R
F
I
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV7
209
23237
S175
A
S
G
T
L
D
V
S
L
N
R
F
I
P
L
Rat
Rattus norvegicus
Q6P4Z9
209
23217
S175
A
P
G
A
L
D
V
S
L
N
R
F
I
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507694
204
22617
S170
K
P
G
A
L
D
V
S
F
N
R
F
I
P
L
Chicken
Gallus gallus
NP_001041472
207
22961
S173
K
P
G
V
L
D
A
S
F
N
R
F
I
P
S
Frog
Xenopus laevis
Q6GQA6
195
21737
M163
Q
A
D
S
A
T
G
M
V
M
P
K
K
P
D
Zebra Danio
Brachydanio rerio
Q7ZUZ0
191
21527
M159
Q
A
D
P
N
T
R
M
I
M
P
Q
K
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTH8
182
21413
I152
E
L
D
G
D
R
V
I
L
K
P
K
V
Q
E
Honey Bee
Apis mellifera
XP_391971
187
21201
P154
V
D
G
T
M
V
Q
P
C
K
I
Q
K
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203845
168
18975
L138
N
S
T
T
Q
M
I
L
P
K
K
P
V
P
S
Poplar Tree
Populus trichocarpa
XP_002298193
199
22672
M168
V
V
D
P
D
S
R
M
L
I
V
K
K
Q
S
Maize
Zea mays
NP_001141592
196
22092
M165
S
L
D
A
A
A
K
M
L
T
V
K
K
P
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43255
197
22528
M166
T
V
D
A
A
S
Q
M
A
S
V
K
K
Q
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
31.6
98
N.A.
95.2
95.6
N.A.
84.2
88
74.1
67.9
N.A.
27.2
46.8
N.A.
43.5
Protein Similarity:
100
96.6
32.2
99.5
N.A.
98
98
N.A.
91.8
93.7
85.1
77.9
N.A.
46.8
63.1
N.A.
63.1
P-Site Identity:
100
100
100
93.3
N.A.
66.6
73.3
N.A.
80
60
13.3
13.3
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
86.6
66.6
20
13.3
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
32.5
32.5
N.A.
33.4
N.A.
N.A.
Protein Similarity:
55.5
52.1
N.A.
53.1
N.A.
N.A.
P-Site Identity:
6.6
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
38
0
50
19
7
7
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
38
0
13
50
0
0
0
0
0
0
0
0
13
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
13
% E
% Phe:
0
0
0
0
0
0
0
0
38
0
0
50
0
0
0
% F
% Gly:
0
0
57
7
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
7
7
7
7
0
50
0
0
% I
% Lys:
13
0
0
0
0
0
7
0
0
19
25
32
38
0
7
% K
% Leu:
0
13
0
0
50
0
0
7
32
0
0
0
0
0
44
% L
% Met:
0
0
0
0
7
7
0
32
0
13
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
0
0
0
50
0
0
0
0
0
% N
% Pro:
0
19
0
13
0
0
0
7
7
0
19
7
0
75
0
% P
% Gln:
13
0
0
0
7
0
13
0
0
0
0
13
0
19
0
% Q
% Arg:
0
0
0
0
0
7
13
0
0
0
32
0
0
0
0
% R
% Ser:
7
13
0
7
0
13
0
50
0
7
0
0
0
0
19
% S
% Thr:
7
0
7
19
0
13
0
0
0
7
0
0
0
0
0
% T
% Val:
38
13
0
7
0
7
50
0
7
0
19
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _