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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHB2
All Species:
12.12
Human Site:
S291
Identified Species:
24.24
UniProt:
Q99623
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99623
NP_001138303.1
299
33296
S291
D
E
S
F
T
R
G
S
D
S
L
I
K
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111919
295
32862
N269
K
T
I
A
T
S
Q
N
R
I
Y
L
T
A
D
Dog
Lupus familis
XP_543843
283
31770
W274
R
M
R
L
C
A
F
W
P
L
A
P
W
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5XIH7
299
33294
S291
D
E
S
F
T
R
G
S
D
S
L
I
K
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN3
301
33318
S291
D
E
G
F
T
R
G
S
D
S
L
L
L
K
Q
Frog
Xenopus laevis
NP_001086635
301
33336
S291
E
D
S
F
T
R
G
S
D
S
L
V
F
K
Q
Zebra Danio
Brachydanio rerio
XP_002662479
303
33767
L290
A
D
S
L
V
M
N
L
Q
D
D
S
F
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24156
276
30365
A248
I
E
A
A
E
D
I
A
Y
Q
L
S
R
S
R
Honey Bee
Apis mellifera
XP_624330
377
42191
D284
P
S
F
D
D
S
S
D
K
L
K
T
S
L
V
Nematode Worm
Caenorhab. elegans
P50093
294
32649
G275
N
K
T
Y
L
P
T
G
G
L
M
L
N
I
A
Sea Urchin
Strong. purpuratus
XP_781225
294
32225
I259
K
I
R
A
A
Q
S
I
A
R
T
I
A
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50085
310
34388
N286
K
I
L
A
S
S
P
N
R
V
I
L
D
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
80.5
N.A.
N.A.
99.6
N.A.
N.A.
94.6
88
80.5
N.A.
47.1
55.9
62.2
69.2
Protein Similarity:
100
N.A.
98.6
84.9
N.A.
N.A.
100
N.A.
N.A.
97.3
96.3
90
N.A.
67.2
67.9
77.9
84.2
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
N.A.
100
N.A.
N.A.
66.6
60
13.3
N.A.
13.3
0
0
6.6
P-Site Similarity:
100
N.A.
20
6.6
N.A.
N.A.
100
N.A.
N.A.
80
86.6
20
N.A.
40
0
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
70.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
34
9
9
0
9
9
0
9
0
9
9
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
17
0
9
9
9
0
9
34
9
9
0
9
0
9
% D
% Glu:
9
34
0
0
9
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
9
34
0
0
9
0
0
0
0
0
17
0
0
% F
% Gly:
0
0
9
0
0
0
34
9
9
0
0
0
0
25
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
17
9
0
0
0
9
9
0
9
9
25
0
9
0
% I
% Lys:
25
9
0
0
0
0
0
0
9
0
9
0
17
17
25
% K
% Leu:
0
0
9
17
9
0
0
9
0
25
42
34
9
9
0
% L
% Met:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
17
0
0
0
0
9
25
0
% N
% Pro:
9
0
0
0
0
9
9
0
9
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
9
9
0
9
9
0
0
0
0
17
% Q
% Arg:
9
0
17
0
0
34
0
0
17
9
0
0
9
0
9
% R
% Ser:
0
9
34
0
9
25
17
34
0
34
0
17
9
9
9
% S
% Thr:
0
9
9
0
42
0
9
0
0
0
9
9
9
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
9
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
9
% W
% Tyr:
0
0
0
9
0
0
0
0
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _