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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHB2 All Species: 29.09
Human Site: S119 Identified Species: 58.18
UniProt: Q99623 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99623 NP_001138303.1 299 33296 S119 P N A Q E L P S M Y Q R L G L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001111919 295 32862 S119 P N A Q E L P S M Y Q R L G L
Dog Lupus familis XP_543843 283 31770 S119 P N A M E L P S M Y Q R L G L
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q5XIH7 299 33294 S119 P N A Q E L P S M Y Q R L G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMN3 301 33318 S119 P N A A E L P S M Y Q R L G L
Frog Xenopus laevis NP_001086635 301 33336 S119 P L A S D L P S L Y Q R L G M
Zebra Danio Brachydanio rerio XP_002662479 303 33767 I127 P L A S N L P I M Y Q Q L G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24156 276 30365 K105 P I P D Q L P K I Y T I L G Q
Honey Bee Apis mellifera XP_624330 377 42191 T112 P D A Q S L P T M Y R Q L G L
Nematode Worm Caenorhab. elegans P50093 294 32649 H118 P N P E H L V H I Y R T L G Q
Sea Urchin Strong. purpuratus XP_781225 294 32225 K118 P V A A D L P K I L Q Q L G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50085 310 34388 T136 P D V V Q L P T I Y R T L G Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 80.5 N.A. N.A. 99.6 N.A. N.A. 94.6 88 80.5 N.A. 47.1 55.9 62.2 69.2
Protein Similarity: 100 N.A. 98.6 84.9 N.A. N.A. 100 N.A. N.A. 97.3 96.3 90 N.A. 67.2 67.9 77.9 84.2
P-Site Identity: 100 N.A. 100 93.3 N.A. N.A. 100 N.A. N.A. 93.3 66.6 60 N.A. 40 66.6 40 46.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. N.A. 100 N.A. N.A. 93.3 86.6 66.6 N.A. 53.3 93.3 60 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 75 17 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 9 17 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 42 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 9 34 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 17 0 0 0 100 0 0 9 9 0 0 100 0 50 % L
% Met: 0 0 0 9 0 0 0 0 59 0 0 0 0 0 9 % M
% Asn: 0 50 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 100 0 17 0 0 0 92 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 34 17 0 0 0 0 0 67 25 0 0 34 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 25 50 0 0 0 % R
% Ser: 0 0 0 17 9 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 17 0 0 9 17 0 0 9 % T
% Val: 0 9 9 9 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _