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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS2IP All Species: 9.39
Human Site: S614 Identified Species: 29.52
UniProt: Q99590 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99590 NP_004710.2 1463 164652 S614 E S P K L E S S E G E I I Q T
Chimpanzee Pan troglodytes XP_001165201 1453 163512 S604 E S P Q L E S S G G E I I Q T
Rhesus Macaque Macaca mulatta XP_001093213 1438 161781 S605 E S P K L K S S E G E I I Q T
Dog Lupus familis XP_534828 1568 176331 S734 V D S P T L E S S E S K I I Q
Cat Felis silvestris
Mouse Mus musculus NP_082424 1456 162081 I639 D S E L P E H I Q T E N T E I
Rat Rattus norvegicus Q63625 1685 184195 D842 P F D P T G S D S S P P S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416047 1361 153147 E555 P V T S P E N E L L E H P E P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694845 1089 120657 Q283 E K R E D E E Q E P E A E N H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 93.5 75.8 N.A. 67.8 20.6 N.A. N.A. 50.7 N.A. 28.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.6 95.5 82.4 N.A. 78.6 35.9 N.A. N.A. 65.8 N.A. 44.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 93.3 13.3 N.A. 20 6.6 N.A. N.A. 13.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 13.3 N.A. 40 13.3 N.A. N.A. 26.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 13 13 0 13 0 0 13 0 0 0 0 0 0 0 % D
% Glu: 50 0 13 13 0 63 25 13 38 13 75 0 13 25 0 % E
% Phe: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 13 0 0 13 38 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 13 0 0 0 0 13 0 0 13 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 0 38 50 13 13 % I
% Lys: 0 13 0 25 0 13 0 0 0 0 0 13 0 0 0 % K
% Leu: 0 0 0 13 38 13 0 0 13 13 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 13 0 0 0 0 13 0 13 0 % N
% Pro: 25 0 38 25 25 0 0 0 0 13 13 13 13 0 13 % P
% Gln: 0 0 0 13 0 0 0 13 13 0 0 0 0 38 13 % Q
% Arg: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 50 13 13 0 0 50 50 25 13 13 0 13 13 13 % S
% Thr: 0 0 13 0 25 0 0 0 0 13 0 0 13 0 38 % T
% Val: 13 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _