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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIT2 All Species: 23.64
Human Site: S13 Identified Species: 40
UniProt: Q99578 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99578 NP_002921.1 217 24668 S13 E A S C S P G S A S G G S R E
Chimpanzee Pan troglodytes XP_001138470 242 27266 S13 E A S C S P G S A S G G S R E
Rhesus Macaque Macaca mulatta XP_001083497 217 24677 S13 E A S C S P G S A S G G S R E
Dog Lupus familis XP_537249 219 25045 S14 P A G S G C G S P A S L S R E
Cat Felis silvestris
Mouse Mus musculus P70425 217 24784 S13 E A H C C P G S S S G G S R E
Rat Rattus norvegicus Q5BJQ5 217 24743 S13 E A H C C P G S S S G G S R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506896 217 24867 S13 E T I C S S S S S S G G S R E
Chicken Gallus gallus XP_001233997 217 24823 N13 E M I S S S S N S S A G S R E
Frog Xenopus laevis Q7ZXH7 184 20815
Zebra Danio Brachydanio rerio Q6TEN1 184 20809
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845
Honey Bee Apis mellifera XP_395139 235 26905 T26 V P V V S Q P T T R C G V R V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783565 275 31241 N15 L V P Q N N N N D L A L T L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P01119 309 34328 L63 K V S I L D I L D T A G Q E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.7 99.5 66.6 N.A. 91.7 91.2 N.A. 89.4 80.6 40 40 N.A. 43.3 53.1 N.A. 45
Protein Similarity: 100 88.4 100 81.2 N.A. 96.3 95.8 N.A. 94.4 91.7 60.3 60.8 N.A. 62.2 67.6 N.A. 58.1
P-Site Identity: 100 100 100 40 N.A. 80 80 N.A. 66.6 46.6 0 0 N.A. 0 20 N.A. 0
P-Site Similarity: 100 100 100 46.6 N.A. 86.6 86.6 N.A. 73.3 60 0 0 N.A. 0 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 43 0 0 0 0 0 0 22 8 22 0 0 0 0 % A
% Cys: 0 0 0 43 15 8 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 15 0 0 0 0 0 0 % D
% Glu: 50 0 0 0 0 0 0 0 0 0 0 0 0 8 65 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 8 0 43 0 0 0 43 65 0 0 8 % G
% His: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 15 8 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 8 0 0 8 0 8 0 15 0 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 8 15 0 0 0 0 0 0 0 % N
% Pro: 8 8 8 0 0 36 8 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 65 0 % R
% Ser: 0 0 29 15 43 15 15 50 29 50 8 0 58 0 0 % S
% Thr: 0 8 0 0 0 0 0 8 8 8 0 0 8 0 0 % T
% Val: 8 15 8 8 0 0 0 0 0 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _