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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLIN2
All Species:
19.39
Human Site:
S374
Identified Species:
47.41
UniProt:
Q99541
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99541
NP_001113.2
437
48075
S374
S
D
S
L
L
T
S
S
K
G
Q
L
Q
K
M
Chimpanzee
Pan troglodytes
XP_520505
553
59993
S482
S
D
G
L
L
T
S
S
K
G
Q
L
Q
K
M
Rhesus Macaque
Macaca mulatta
XP_001110076
437
47994
S374
S
D
S
L
L
T
S
S
K
G
Q
L
Q
K
M
Dog
Lupus familis
XP_531946
437
47910
S374
S
D
S
L
L
T
S
S
K
G
Q
L
Q
K
M
Cat
Felis silvestris
Mouse
Mus musculus
P43883
425
46646
E363
R
N
A
A
S
F
K
E
V
S
D
G
V
L
T
Rat
Rattus norvegicus
NP_001007145
422
46245
E360
R
N
V
T
S
F
K
E
V
S
D
G
V
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508681
585
64391
S522
S
A
G
L
L
T
S
S
K
G
Q
L
H
K
M
Chicken
Gallus gallus
NP_001026591
431
47227
S368
A
S
S
F
Q
E
L
S
D
S
F
L
T
T
S
Frog
Xenopus laevis
NP_001087955
404
44394
V342
S
A
S
S
L
K
E
V
S
D
N
L
L
T
N
Zebra Danio
Brachydanio rerio
NP_001025433
428
47057
S366
A
A
V
L
G
D
L
S
S
T
V
L
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73
95.8
89.6
N.A.
81
78.4
N.A.
42.3
71.1
58.1
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.9
97
95.8
N.A.
90.3
89.2
N.A.
56
88
73.4
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
0
0
N.A.
80
20
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
13.3
6.6
N.A.
80
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
30
10
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
0
0
0
10
0
0
10
10
20
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
20
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
20
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
20
0
10
0
0
0
0
50
0
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
20
0
50
0
0
0
0
50
0
% K
% Leu:
0
0
0
60
60
0
20
0
0
0
0
80
10
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
50
0
40
0
0
% Q
% Arg:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
60
10
50
10
20
0
50
70
20
30
0
0
10
10
20
% S
% Thr:
0
0
0
10
0
50
0
0
0
10
0
0
10
20
20
% T
% Val:
0
0
20
0
0
0
0
10
20
0
10
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _