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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD1
All Species:
36.97
Human Site:
Y460
Identified Species:
62.56
UniProt:
Q99460
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99460
NP_002798.2
953
105836
Y460
H
G
G
D
I
I
D
Y
L
L
N
Q
L
K
N
Chimpanzee
Pan troglodytes
XP_526057
959
106478
Y466
H
G
G
D
I
I
D
Y
L
L
N
Q
L
K
N
Rhesus Macaque
Macaca mulatta
XP_001113035
953
105815
Y460
H
G
G
D
I
I
D
Y
L
L
N
Q
L
K
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3TXS7
953
105712
Y460
H
G
G
D
I
I
D
Y
L
L
N
Q
L
K
N
Rat
Rattus norvegicus
O88761
953
105730
Y460
H
G
G
D
I
I
D
Y
L
L
N
Q
L
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508583
702
77639
A290
I
F
L
D
D
P
Q
A
V
S
D
I
L
E
K
Chicken
Gallus gallus
Q5F418
955
106044
Y460
H
G
G
D
I
I
D
Y
L
L
N
Q
L
K
N
Frog
Xenopus laevis
NP_001089647
951
105440
Y460
H
G
G
D
I
I
D
Y
L
L
N
Q
L
K
N
Zebra Danio
Brachydanio rerio
NP_957478
887
99599
Y461
H
G
G
D
I
I
D
Y
L
L
S
Q
L
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3P6
1020
113180
Y475
H
G
A
N
I
I
D
Y
L
L
Q
Q
L
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18115
965
105990
T438
G
D
A
T
A
M
S
T
L
A
Q
W
L
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323770
1006
109351
F477
H
G
E
G
I
K
Q
F
L
R
E
S
I
R
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_180832
1004
108959
F471
H
G
E
G
I
K
Q
F
L
R
D
S
L
R
S
Baker's Yeast
Sacchar. cerevisiae
P32565
945
104214
E429
Y
L
K
N
I
I
V
E
N
S
G
T
S
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.7
N.A.
N.A.
99
98.6
N.A.
64.6
97
94.2
80.4
N.A.
63.7
N.A.
35.3
N.A.
Protein Similarity:
100
99.2
99.9
N.A.
N.A.
99.5
99.2
N.A.
65.7
98.4
97.4
86.1
N.A.
78.2
N.A.
56.1
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
13.3
100
100
93.3
N.A.
73.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
33.3
100
100
100
N.A.
86.6
N.A.
26.6
N.A.
Percent
Protein Identity:
49.5
N.A.
N.A.
50
42.7
N.A.
Protein Similarity:
67.2
N.A.
N.A.
67.9
61.1
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
8
0
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
65
8
0
65
0
0
0
15
0
0
0
15
% D
% Glu:
0
0
15
0
0
0
0
8
0
0
8
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
8
79
58
15
0
0
0
0
0
0
8
0
0
8
0
% G
% His:
79
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
86
72
0
0
0
0
0
8
8
0
0
% I
% Lys:
0
0
8
0
0
15
0
0
0
0
0
0
0
72
8
% K
% Leu:
0
8
8
0
0
0
0
0
86
65
0
0
86
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
0
8
0
50
0
0
0
58
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
22
0
0
0
15
65
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
15
0
0
0
15
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
15
8
15
8
0
15
% S
% Thr:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
8
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _