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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD1 All Species: 20
Human Site: T322 Identified Species: 33.85
UniProt: Q99460 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99460 NP_002798.2 953 105836 T322 S P E P K D Q T L K M I K I L
Chimpanzee Pan troglodytes XP_526057 959 106478 T328 S P E P K D Q T L K M I K I L
Rhesus Macaque Macaca mulatta XP_001113035 953 105815 T322 S P E P K D Q T L K M I K I L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3TXS7 953 105712 T322 S P E P K D Q T L K M I K I L
Rat Rattus norvegicus O88761 953 105730 T322 S P E P K D Q T L K M I K I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508583 702 77639 V159 V N D N S E Y V E T I I A K C
Chicken Gallus gallus Q5F418 955 106044 I322 N P E P K D Q I S K M I K I L
Frog Xenopus laevis NP_001089647 951 105440 I322 N P E P K D Q I S K M V K I L
Zebra Danio Brachydanio rerio NP_957478 887 99599 N323 K D E P K D Q N S K M I K I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3P6 1020 113180 S325 K V E R T I D S L N E V E K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18115 965 105990 K301 R D E K S M E K I H S I L K G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002323770 1006 109351 A330 D P S E V V Y A E R L T K I K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_180832 1004 108959 L329 D A T Y A E R L T K I K G I L
Baker's Yeast Sacchar. cerevisiae P32565 945 104214 L286 A Q G Y D P A L L N I L S G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 99.7 N.A. N.A. 99 98.6 N.A. 64.6 97 94.2 80.4 N.A. 63.7 N.A. 35.3 N.A.
Protein Similarity: 100 99.2 99.9 N.A. N.A. 99.5 99.2 N.A. 65.7 98.4 97.4 86.1 N.A. 78.2 N.A. 56.1 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 6.6 80 73.3 73.3 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 26.6 86.6 86.6 73.3 N.A. 40 N.A. 26.6 N.A.
Percent
Protein Identity: 49.5 N.A. N.A. 50 42.7 N.A.
Protein Similarity: 67.2 N.A. N.A. 67.9 61.1 N.A.
P-Site Identity: 20 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 8 0 8 8 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 15 15 8 0 8 58 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 72 8 0 15 8 0 15 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 15 8 0 22 65 0 72 0 % I
% Lys: 15 0 0 8 58 0 0 8 0 65 0 8 65 22 8 % K
% Leu: 0 0 0 0 0 0 0 15 50 0 8 8 8 0 79 % L
% Met: 0 0 0 0 0 8 0 0 0 0 58 0 0 0 0 % M
% Asn: 15 8 0 8 0 0 0 8 0 15 0 0 0 0 0 % N
% Pro: 0 58 0 58 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 58 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % R
% Ser: 36 0 8 0 15 0 0 8 22 0 8 0 8 0 0 % S
% Thr: 0 0 8 0 8 0 0 36 8 8 0 8 0 0 0 % T
% Val: 8 8 0 0 8 8 0 8 0 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 15 0 0 15 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _