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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD1 All Species: 49.09
Human Site: S643 Identified Species: 83.08
UniProt: Q99460 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99460 NP_002798.2 953 105836 S643 V V S L L S E S Y N P H V R Y
Chimpanzee Pan troglodytes XP_526057 959 106478 S649 V V S L L S E S Y N P H V R Y
Rhesus Macaque Macaca mulatta XP_001113035 953 105815 S643 V V S L L S E S Y N P H V R Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3TXS7 953 105712 S643 V V S L L S E S Y N P H V R Y
Rat Rattus norvegicus O88761 953 105730 S643 V V S L L S E S Y N P H V R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508583 702 77639 L470 K F T A T A S L G V I H K G H
Chicken Gallus gallus Q5F418 955 106044 S643 V V S L L S E S Y N P H V R Y
Frog Xenopus laevis NP_001089647 951 105440 S643 V V S L L S E S Y N P H V R Y
Zebra Danio Brachydanio rerio NP_957478 887 99599 S644 V V S L L S E S Y N P H V R Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3P6 1020 113180 S658 V V S L L A E S Y N P H V R Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18115 965 105990 H622 Y V A M L T E H F N G H V R Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002323770 1006 109351 S659 I V S L L S E S Y N P H V R Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_180832 1004 108959 S653 I V S L L S E S Y N P H V R Y
Baker's Yeast Sacchar. cerevisiae P32565 945 104214 S612 I V Q L L S K S H N A H V R C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 99.7 N.A. N.A. 99 98.6 N.A. 64.6 97 94.2 80.4 N.A. 63.7 N.A. 35.3 N.A.
Protein Similarity: 100 99.2 99.9 N.A. N.A. 99.5 99.2 N.A. 65.7 98.4 97.4 86.1 N.A. 78.2 N.A. 56.1 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 6.6 100 100 100 N.A. 93.3 N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 26.6 100 100 100 N.A. 100 N.A. 80 N.A.
Percent
Protein Identity: 49.5 N.A. N.A. 50 42.7 N.A.
Protein Similarity: 67.2 N.A. N.A. 67.9 61.1 N.A.
P-Site Identity: 93.3 N.A. N.A. 93.3 60 N.A.
P-Site Similarity: 100 N.A. N.A. 100 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 15 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 86 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 8 0 0 100 0 0 8 % H
% Ile: 22 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 86 93 0 0 8 0 0 0 0 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 93 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 79 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 % R
% Ser: 0 0 79 0 0 79 8 86 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 8 8 0 0 0 0 0 0 0 0 0 % T
% Val: 65 93 0 0 0 0 0 0 0 8 0 0 93 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 79 0 0 0 0 0 86 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _