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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT12
All Species:
5.45
Human Site:
T465
Identified Species:
15
UniProt:
Q99456
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99456
NP_000214.1
494
53511
T465
T
D
S
S
K
D
P
T
K
T
R
K
I
K
T
Chimpanzee
Pan troglodytes
A5A6M0
432
48102
T405
Y
K
K
E
P
V
T
T
R
Q
V
R
T
I
V
Rhesus Macaque
Macaca mulatta
XP_001101582
495
53630
T466
T
D
S
S
K
D
P
T
K
T
R
K
I
K
T
Dog
Lupus familis
XP_548099
469
51329
V440
Q
P
T
R
E
A
T
V
T
T
R
Q
V
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q64291
487
52446
N458
V
D
S
S
K
D
P
N
K
T
R
K
I
K
T
Rat
Rattus norvegicus
Q6IFW5
456
48802
N427
V
D
S
S
K
D
P
N
K
T
R
K
I
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520530
452
49640
G424
V
E
E
I
D
Q
R
G
K
V
L
S
S
R
V
Chicken
Gallus gallus
O93256
423
46064
Q396
Q
E
I
A
T
Y
R
Q
L
L
E
G
Q
E
S
Frog
Xenopus laevis
P05781
419
45634
G392
T
Y
R
R
L
L
E
G
E
F
G
S
L
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.6
97.7
55.2
N.A.
77.5
74.9
N.A.
49.7
52
53.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.4
98.7
68.8
N.A.
84.4
79.3
N.A.
64.9
65.9
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
20
N.A.
86.6
86.6
N.A.
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
53.3
N.A.
86.6
86.6
N.A.
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
45
0
0
12
45
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
23
12
12
12
0
12
0
12
0
12
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
23
0
0
12
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
12
0
0
0
0
0
0
0
0
45
12
0
% I
% Lys:
0
12
12
0
45
0
0
0
56
0
0
45
0
56
0
% K
% Leu:
0
0
0
0
12
12
0
0
12
12
12
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
12
0
45
0
0
0
0
0
0
0
0
% P
% Gln:
23
0
0
0
0
12
0
12
0
12
0
12
12
0
0
% Q
% Arg:
0
0
12
23
0
0
23
0
12
0
56
12
0
23
0
% R
% Ser:
0
0
45
45
0
0
0
0
0
0
0
23
12
0
23
% S
% Thr:
34
0
12
0
12
0
23
34
12
56
0
0
12
0
56
% T
% Val:
34
0
0
0
0
12
0
12
0
12
12
0
12
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _