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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNN2
All Species:
16.67
Human Site:
Y273
Identified Species:
30.56
UniProt:
Q99439
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99439
NP_004359.1
309
33697
Y273
R
Q
I
Y
D
P
K
Y
C
P
Q
G
T
V
A
Chimpanzee
Pan troglodytes
XP_001156976
309
33707
Y273
R
Q
I
Y
D
P
K
Y
C
P
Q
G
T
V
A
Rhesus Macaque
Macaca mulatta
XP_001110773
309
33749
Y273
R
Q
I
Y
D
P
K
Y
C
P
Q
G
T
V
A
Dog
Lupus familis
XP_854646
309
33368
Y273
R
Q
I
Y
D
P
K
Y
C
P
Q
G
P
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q08093
305
33137
D270
G
L
G
R
Q
I
Y
D
P
K
Y
C
P
Q
G
Rat
Rattus norvegicus
P37397
330
36416
Q286
P
V
I
H
N
G
S
Q
G
T
G
T
N
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521357
371
41328
K313
G
R
Q
V
Y
D
P
K
Y
C
A
A
P
T
E
Chicken
Gallus gallus
P26932
292
32342
G257
N
K
G
A
S
Q
Q
G
M
T
V
Y
G
L
P
Frog
Xenopus laevis
NP_001085881
295
32821
I260
G
A
N
Q
S
G
Q
I
F
G
L
G
R
Q
I
Zebra Danio
Brachydanio rerio
NP_998514
307
33822
Y272
R
Q
I
Y
D
A
K
Y
C
P
K
G
G
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P14318
184
20172
Q149
K
R
D
F
T
E
E
Q
L
K
A
G
Q
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P37806
565
62709
Q451
K
G
M
T
G
F
G
Q
P
R
W
E
V
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08873
200
22730
K165
P
P
V
K
S
K
P
K
H
L
Q
D
G
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
94.5
N.A.
94.8
63.3
N.A.
54.7
58.2
78.6
72.8
N.A.
23.2
N.A.
21.7
N.A.
Protein Similarity:
100
100
98.3
95.1
N.A.
95.7
74.2
N.A.
64.6
72.8
85.1
81.2
N.A.
36.5
N.A.
33
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
6.6
N.A.
0
0
6.6
66.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
0
26.6
N.A.
6.6
20
13.3
73.3
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
0
0
0
0
16
8
0
8
31
% A
% Cys:
0
0
0
0
0
0
0
0
39
8
0
8
0
0
0
% C
% Asp:
0
0
8
0
39
8
0
8
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
8
% E
% Phe:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% F
% Gly:
24
8
16
0
8
16
8
8
8
8
8
54
24
8
16
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
47
0
0
8
0
8
0
0
0
0
0
0
16
% I
% Lys:
16
8
0
8
0
8
39
16
0
16
8
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
8
8
8
0
0
16
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
16
8
0
0
0
31
16
0
16
39
0
0
24
0
8
% P
% Gln:
0
39
8
8
8
8
16
24
0
0
39
0
8
16
0
% Q
% Arg:
39
16
0
8
0
0
0
0
0
8
0
0
8
0
0
% R
% Ser:
0
0
0
0
24
0
8
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
8
8
0
0
0
0
16
0
8
24
24
0
% T
% Val:
0
8
8
8
0
0
0
0
0
0
8
0
8
31
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
39
8
0
8
39
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _