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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNN2 All Species: 24.24
Human Site: S246 Identified Species: 44.44
UniProt: Q99439 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99439 NP_004359.1 309 33697 S246 K C D N S S M S L Q M G Y T Q
Chimpanzee Pan troglodytes XP_001156976 309 33707 S246 K C D N S S M S L Q M G Y T Q
Rhesus Macaque Macaca mulatta XP_001110773 309 33749 S246 K C D N S S M S L Q M G Y T Q
Dog Lupus familis XP_854646 309 33368 S246 K C D N S S M S L Q M G Y T Q
Cat Felis silvestris
Mouse Mus musculus Q08093 305 33137 S243 G T D K C D N S S M S L Q M G
Rat Rattus norvegicus P37397 330 36416 S259 V A S Q K G M S V Y G L G R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521357 371 41328 S286 P V D N S T I S L Q M G T N K
Chicken Gallus gallus P26932 292 32342 E230 G T K R Q I F E P S L G M E R
Frog Xenopus laevis NP_001085881 295 32821 K233 R R H I Y D T K S G T E K C D
Zebra Danio Brachydanio rerio NP_998514 307 33822 S245 K C D N S T M S L Q M G Y S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14318 184 20172 T122 I F A L G R A T Y K H A D F K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P37806 565 62709 C424 H P D Y S H E C S I D Q T T I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08873 200 22730 K138 S L S R Y A N K K H T D R F P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 94.5 N.A. 94.8 63.3 N.A. 54.7 58.2 78.6 72.8 N.A. 23.2 N.A. 21.7 N.A.
Protein Similarity: 100 100 98.3 95.1 N.A. 95.7 74.2 N.A. 64.6 72.8 85.1 81.2 N.A. 36.5 N.A. 33 N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 20 N.A. 53.3 6.6 0 86.6 N.A. 0 N.A. 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 13.3 26.6 N.A. 73.3 20 6.6 100 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 8 0 0 0 0 8 0 0 0 % A
% Cys: 0 39 0 0 8 0 0 8 0 0 0 0 0 8 0 % C
% Asp: 0 0 62 0 0 16 0 0 0 0 8 8 8 0 8 % D
% Glu: 0 0 0 0 0 0 8 8 0 0 0 8 0 8 0 % E
% Phe: 0 8 0 0 0 0 8 0 0 0 0 0 0 16 0 % F
% Gly: 16 0 0 0 8 8 0 0 0 8 8 54 8 0 8 % G
% His: 8 0 8 0 0 8 0 0 0 8 8 0 0 0 0 % H
% Ile: 8 0 0 8 0 8 8 0 0 8 0 0 0 0 8 % I
% Lys: 39 0 8 8 8 0 0 16 8 8 0 0 8 0 16 % K
% Leu: 0 8 0 8 0 0 0 0 47 0 8 16 0 0 0 % L
% Met: 0 0 0 0 0 0 47 0 0 8 47 0 8 8 0 % M
% Asn: 0 0 0 47 0 0 16 0 0 0 0 0 0 8 0 % N
% Pro: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 8 % P
% Gln: 0 0 0 8 8 0 0 0 0 47 0 8 8 0 47 % Q
% Arg: 8 8 0 16 0 8 0 0 0 0 0 0 8 8 8 % R
% Ser: 8 0 16 0 54 31 0 62 24 8 8 0 0 8 0 % S
% Thr: 0 16 0 0 0 16 8 8 0 0 16 0 16 39 0 % T
% Val: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 16 0 0 0 8 8 0 0 39 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _