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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX2
All Species:
40.91
Human Site:
Y280
Identified Species:
64.29
UniProt:
Q99424
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99424
NP_003491.1
681
76827
Y280
Q
V
L
P
D
G
T
Y
V
K
L
G
T
A
Q
Chimpanzee
Pan troglodytes
XP_001174257
681
76735
Y280
Q
V
L
P
D
G
T
Y
V
K
L
G
T
A
Q
Rhesus Macaque
Macaca mulatta
XP_001102134
660
74475
Y265
Q
V
K
P
D
G
T
Y
V
K
P
L
S
N
K
Dog
Lupus familis
XP_541826
664
74511
Y280
Q
V
L
P
D
G
T
Y
L
K
V
G
S
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXD1
681
76874
Y280
E
V
L
P
D
G
T
Y
Q
R
L
G
T
P
Q
Rat
Rattus norvegicus
P97562
681
76780
Y280
E
V
L
P
D
G
T
Y
Q
R
L
G
T
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514051
633
70993
R254
Y
G
T
M
V
F
I
R
S
I
L
V
G
E
A
Chicken
Gallus gallus
XP_414406
675
75475
Y280
E
V
Q
P
D
G
T
Y
V
R
R
G
S
Q
K
Frog
Xenopus laevis
NP_001084533
670
74874
Y275
E
V
L
P
D
G
T
Y
V
K
R
G
S
D
K
Zebra Danio
Brachydanio rerio
NP_001005933
660
74026
Y265
Q
V
E
P
D
G
T
Y
V
K
P
P
S
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
Y278
Q
V
L
P
D
G
T
Y
V
A
P
K
N
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34355
659
74696
Y277
K
V
S
K
E
G
L
Y
T
A
P
S
H
P
K
Sea Urchin
Strong. purpuratus
XP_783450
682
76709
Y286
K
V
M
P
D
G
T
Y
V
P
P
P
H
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65202
664
74283
Y267
K
V
T
R
E
G
E
Y
V
P
S
D
V
P
K
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
G315
K
V
V
R
S
P
D
G
S
V
T
V
K
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
44.3
76.6
N.A.
73.2
73.7
N.A.
40.5
57.5
54.6
44.4
N.A.
36.1
N.A.
32.8
43.2
Protein Similarity:
100
99.5
62.4
86
N.A.
84.8
83.8
N.A.
58.4
74
69.9
63.8
N.A.
52.7
N.A.
55
60.1
P-Site Identity:
100
100
60
73.3
N.A.
73.3
73.3
N.A.
6.6
53.3
66.6
60
N.A.
60
N.A.
20
46.6
P-Site Similarity:
100
100
73.3
93.3
N.A.
86.6
86.6
N.A.
6.6
80
86.6
73.3
N.A.
66.6
N.A.
40
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.6
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
14
0
0
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
74
0
7
0
0
0
0
7
0
14
0
% D
% Glu:
27
0
7
0
14
0
7
0
0
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
87
0
7
0
0
0
47
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% I
% Lys:
27
0
7
7
0
0
0
0
0
40
0
7
7
7
47
% K
% Leu:
0
0
47
0
0
0
7
0
7
0
34
7
0
7
0
% L
% Met:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
74
0
7
0
0
0
14
34
14
0
27
0
% P
% Gln:
40
0
7
0
0
0
0
0
14
0
0
0
0
7
34
% Q
% Arg:
0
0
0
14
0
0
0
7
0
20
14
0
0
0
0
% R
% Ser:
0
0
7
0
7
0
0
0
14
0
7
7
34
7
0
% S
% Thr:
0
0
14
0
0
0
74
0
7
0
7
0
27
7
0
% T
% Val:
0
94
7
0
7
0
0
0
60
7
7
14
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _