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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX2
All Species:
18.79
Human Site:
T37
Identified Species:
29.52
UniProt:
Q99424
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99424
NP_003491.1
681
76827
T37
S
F
D
V
E
R
L
T
N
I
L
D
G
G
A
Chimpanzee
Pan troglodytes
XP_001174257
681
76735
T37
S
F
D
V
E
R
L
T
N
I
L
D
G
G
A
Rhesus Macaque
Macaca mulatta
XP_001102134
660
74475
E37
T
R
R
R
R
E
I
E
N
M
I
L
N
D
P
Dog
Lupus familis
XP_541826
664
74511
I37
S
F
N
V
E
R
L
I
N
I
L
D
G
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXD1
681
76874
T37
S
F
S
V
E
R
L
T
N
I
L
D
G
G
I
Rat
Rattus norvegicus
P97562
681
76780
T37
S
F
S
V
E
R
L
T
N
I
L
D
G
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514051
633
70993
K38
R
Y
E
L
A
V
K
K
S
A
D
M
V
K
K
Chicken
Gallus gallus
XP_414406
675
75475
T37
S
F
C
V
P
R
L
T
A
V
L
D
G
G
A
Frog
Xenopus laevis
NP_001084533
670
74874
K41
L
L
D
G
S
V
D
K
T
R
L
R
R
Y
V
Zebra Danio
Brachydanio rerio
NP_001005933
660
74026
E37
T
N
R
R
R
E
I
E
S
L
V
I
G
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
K38
G
E
E
R
F
K
E
K
K
A
L
E
K
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34355
659
74696
K41
H
G
G
E
D
A
L
K
R
I
R
E
L
R
D
Sea Urchin
Strong. purpuratus
XP_783450
682
76709
T40
K
F
D
P
I
E
L
T
Y
V
I
D
G
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65202
664
74283
A39
F
E
V
S
D
R
I
A
R
L
V
A
S
D
P
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
E39
D
Q
V
N
T
F
L
E
S
S
P
E
R
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
44.3
76.6
N.A.
73.2
73.7
N.A.
40.5
57.5
54.6
44.4
N.A.
36.1
N.A.
32.8
43.2
Protein Similarity:
100
99.5
62.4
86
N.A.
84.8
83.8
N.A.
58.4
74
69.9
63.8
N.A.
52.7
N.A.
55
60.1
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
0
73.3
13.3
6.6
N.A.
6.6
N.A.
13.3
46.6
P-Site Similarity:
100
100
33.3
93.3
N.A.
86.6
86.6
N.A.
26.6
80
13.3
40
N.A.
26.6
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.6
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
7
7
14
0
7
0
0
27
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
27
0
14
0
7
0
0
0
7
47
0
20
7
% D
% Glu:
0
14
14
7
34
20
7
20
0
0
0
20
0
0
0
% E
% Phe:
7
47
0
0
7
7
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
7
7
7
0
0
0
0
0
0
0
0
54
47
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
20
7
0
40
14
7
0
0
7
% I
% Lys:
7
0
0
0
0
7
7
27
7
0
0
0
7
7
14
% K
% Leu:
7
7
0
7
0
0
60
0
0
14
54
7
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
0
7
7
7
0
0
0
0
40
0
0
0
7
0
0
% N
% Pro:
0
0
0
7
7
0
0
0
0
0
7
0
0
0
20
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
14
20
14
47
0
0
14
7
7
7
14
14
0
% R
% Ser:
40
0
14
7
7
0
0
0
20
7
0
0
7
0
0
% S
% Thr:
14
0
0
0
7
0
0
40
7
0
0
0
0
0
7
% T
% Val:
0
0
14
40
0
14
0
0
0
14
14
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _