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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX2
All Species:
43.33
Human Site:
S421
Identified Species:
68.1
UniProt:
Q99424
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99424
NP_003491.1
681
76827
S421
G
H
G
Y
S
K
L
S
G
L
P
S
L
V
T
Chimpanzee
Pan troglodytes
XP_001174257
681
76735
S421
G
H
G
Y
S
K
L
S
G
L
P
S
L
V
T
Rhesus Macaque
Macaca mulatta
XP_001102134
660
74475
S405
G
H
G
Y
S
H
C
S
G
L
P
N
I
Y
V
Dog
Lupus familis
XP_541826
664
74511
S421
G
H
G
Y
S
K
L
S
G
L
P
S
L
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXD1
681
76874
S421
G
H
G
Y
S
K
L
S
G
L
P
T
L
V
T
Rat
Rattus norvegicus
P97562
681
76780
S421
G
H
G
Y
S
K
L
S
G
L
P
T
L
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514051
633
70993
E393
F
T
P
S
C
T
Y
E
G
E
N
T
V
M
M
Chicken
Gallus gallus
XP_414406
675
75475
S421
G
H
G
Y
S
L
L
S
G
L
P
S
L
Y
T
Frog
Xenopus laevis
NP_001084533
670
74874
S416
G
H
G
Y
S
L
F
S
G
L
P
S
L
Y
T
Zebra Danio
Brachydanio rerio
NP_001005933
660
74026
S405
G
H
G
Y
S
R
C
S
S
L
P
D
I
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
S418
G
H
G
Y
M
D
C
S
N
F
P
T
I
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34355
659
74696
S417
G
H
G
Y
S
D
A
S
Y
L
P
T
L
Y
T
Sea Urchin
Strong. purpuratus
XP_783450
682
76709
S426
G
H
G
Y
S
K
A
S
G
F
P
E
L
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65202
664
74283
S408
G
H
G
Y
L
W
C
S
G
L
P
E
L
F
A
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
N472
G
H
G
Y
S
Q
Y
N
G
F
G
K
G
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
44.3
76.6
N.A.
73.2
73.7
N.A.
40.5
57.5
54.6
44.4
N.A.
36.1
N.A.
32.8
43.2
Protein Similarity:
100
99.5
62.4
86
N.A.
84.8
83.8
N.A.
58.4
74
69.9
63.8
N.A.
52.7
N.A.
55
60.1
P-Site Identity:
100
100
60
93.3
N.A.
93.3
86.6
N.A.
6.6
86.6
80
53.3
N.A.
40
N.A.
66.6
66.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
93.3
N.A.
26.6
86.6
80
66.6
N.A.
53.3
N.A.
73.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.6
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
14
% A
% Cys:
0
0
0
0
7
0
27
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
14
0
0
0
0
0
7
0
0
7
% D
% Glu:
0
0
0
0
0
0
0
7
0
7
0
14
0
0
0
% E
% Phe:
7
0
0
0
0
0
7
0
0
20
0
0
0
7
0
% F
% Gly:
94
0
94
0
0
0
0
0
80
0
7
0
7
0
14
% G
% His:
0
94
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
40
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
0
7
14
40
0
0
74
0
0
67
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
7
7
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
87
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
80
0
0
87
7
0
0
34
0
0
7
% S
% Thr:
0
7
0
0
0
7
0
0
0
0
0
34
0
0
40
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
34
14
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
94
0
0
14
0
7
0
0
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _