KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HBEGF
All Species:
22.03
Human Site:
S6
Identified Species:
60.58
UniProt:
Q99075
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99075
NP_001936.1
208
23067
S6
_
_
M
K
L
L
P
S
V
V
L
K
L
F
L
Chimpanzee
Pan troglodytes
XP_001137119
208
23062
S6
_
_
M
K
L
L
P
S
V
V
L
K
L
F
L
Rhesus Macaque
Macaca mulatta
XP_001085848
208
22965
S6
_
_
M
K
L
L
P
S
V
V
L
K
L
L
L
Dog
Lupus familis
XP_848614
208
22956
S6
_
_
M
K
L
L
R
S
V
V
L
K
L
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q06186
208
22789
S6
_
_
M
K
L
L
P
S
V
M
L
K
L
F
L
Rat
Rattus norvegicus
Q06175
208
22824
S6
_
_
M
K
L
L
P
S
V
V
L
K
L
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521858
373
40154
R169
P
G
P
H
E
G
S
R
G
C
G
R
T
G
I
Chicken
Gallus gallus
Q5EG71
151
17011
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104696
230
25617
A20
T
I
V
A
V
R
G
A
S
I
P
L
V
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.6
88.9
N.A.
80.7
81.7
N.A.
39.9
22.6
N.A.
43.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98
92.3
N.A.
90.3
91.8
N.A.
46.6
40.3
N.A.
57.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
92.3
92.3
N.A.
92.3
100
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
92.3
92.3
N.A.
100
100
N.A.
20
0
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% F
% Gly:
0
12
0
0
0
12
12
0
12
0
12
0
0
12
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
12
% I
% Lys:
0
0
0
67
0
0
0
0
0
0
0
67
0
0
0
% K
% Leu:
0
0
0
0
67
67
0
0
0
0
67
12
67
12
67
% L
% Met:
0
0
67
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
12
0
0
0
56
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
12
12
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
0
0
0
12
67
12
0
0
0
0
0
0
% S
% Thr:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% T
% Val:
0
0
12
0
12
0
0
0
67
56
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
67
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% _