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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIN3A All Species: 34.24
Human Site: Y62 Identified Species: 68.48
UniProt: Q96ST3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96ST3 NP_001138829.1 1273 145175 Y62 Q Y S V T P S Y Q V S A M P Q
Chimpanzee Pan troglodytes XP_510682 1273 145185 Y62 Q Y S V T P S Y Q V S A M P Q
Rhesus Macaque Macaca mulatta XP_001103539 1273 145217 Y62 Q Y S V T P S Y Q V S A M P Q
Dog Lupus familis XP_535546 1240 141674 Y62 Q Y S V T P S Y Q V S A V P Q
Cat Felis silvestris
Mouse Mus musculus Q60520 1282 146164 Y62 Q Y S V A P N Y Q V S A V P Q
Rat Rattus norvegicus NP_001102231 1129 127784 Q16 E S P V Y A A Q Q R R I P G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512119 1268 144524 Y62 Q Y S V T P S Y Q V S S V G R
Chicken Gallus gallus XP_413695 1272 145279 Y62 Q Y S V T P S Y Q V G L P R P
Frog Xenopus laevis NP_001081937 1275 145070 Y59 Q Y S V A P G Y Q V S A V P Q
Zebra Danio Brachydanio rerio NP_001091650 1276 145765 Y59 Q Y P L P Q A Y Q V S T V A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188916 1290 146297 Y63 H Y Q P M P G Y S V P A V G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22579 1536 174821 H103 D S A L K Q P H E Y H P R P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.8 96.4 N.A. 97.4 86.8 N.A. 90.8 91.1 82.3 78 N.A. N.A. N.A. N.A. 53
Protein Similarity: 100 99.9 99.8 96.9 N.A. 98.4 87.7 N.A. 94.9 94.9 89.5 86.9 N.A. N.A. N.A. N.A. 67.5
P-Site Identity: 100 100 100 93.3 N.A. 80 13.3 N.A. 73.3 66.6 80 46.6 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 26.6 N.A. 93.3 66.6 86.6 66.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 17 9 17 0 0 0 0 59 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 17 0 0 0 9 0 0 25 0 % G
% His: 9 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 17 0 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 25 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 9 9 75 9 0 0 0 9 9 17 59 9 % P
% Gln: 75 0 9 0 0 17 0 9 84 0 0 0 0 0 67 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 9 0 9 9 9 % R
% Ser: 0 17 67 0 0 0 50 0 9 0 67 9 0 0 9 % S
% Thr: 0 0 0 0 50 0 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 75 0 0 0 0 0 84 0 0 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 84 0 0 9 0 0 84 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _