KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3A
All Species:
28.48
Human Site:
S65
Identified Species:
56.97
UniProt:
Q96ST3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96ST3
NP_001138829.1
1273
145175
S65
V
T
P
S
Y
Q
V
S
A
M
P
Q
S
S
G
Chimpanzee
Pan troglodytes
XP_510682
1273
145185
S65
V
T
P
S
Y
Q
V
S
A
M
P
Q
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001103539
1273
145217
S65
V
T
P
S
Y
Q
V
S
A
M
P
Q
S
S
G
Dog
Lupus familis
XP_535546
1240
141674
S65
V
T
P
S
Y
Q
V
S
A
V
P
Q
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60520
1282
146164
S65
V
A
P
N
Y
Q
V
S
A
V
P
Q
S
S
G
Rat
Rattus norvegicus
NP_001102231
1129
127784
R19
V
Y
A
A
Q
Q
R
R
I
P
G
S
T
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512119
1268
144524
S65
V
T
P
S
Y
Q
V
S
S
V
G
R
A
V
P
Chicken
Gallus gallus
XP_413695
1272
145279
G65
V
T
P
S
Y
Q
V
G
L
P
R
P
G
G
G
Frog
Xenopus laevis
NP_001081937
1275
145070
S62
V
A
P
G
Y
Q
V
S
A
V
P
Q
S
S
G
Zebra Danio
Brachydanio rerio
NP_001091650
1276
145765
S62
L
P
Q
A
Y
Q
V
S
T
V
A
Q
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
P66
P
M
P
G
Y
S
V
P
A
V
G
Q
P
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
H106
L
K
Q
P
H
E
Y
H
P
R
P
K
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.8
96.4
N.A.
97.4
86.8
N.A.
90.8
91.1
82.3
78
N.A.
N.A.
N.A.
N.A.
53
Protein Similarity:
100
99.9
99.8
96.9
N.A.
98.4
87.7
N.A.
94.9
94.9
89.5
86.9
N.A.
N.A.
N.A.
N.A.
67.5
P-Site Identity:
100
100
100
93.3
N.A.
80
13.3
N.A.
53.3
53.3
80
46.6
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
80
53.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
17
0
0
0
0
59
0
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
9
0
0
25
0
9
9
59
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
17
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
25
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
9
75
9
0
0
0
9
9
17
59
9
9
0
9
% P
% Gln:
0
0
17
0
9
84
0
0
0
0
0
67
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
9
0
9
9
9
0
0
0
% R
% Ser:
0
0
0
50
0
9
0
67
9
0
0
9
67
67
25
% S
% Thr:
0
50
0
0
0
0
0
0
9
0
0
0
9
0
0
% T
% Val:
75
0
0
0
0
0
84
0
0
50
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
84
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _