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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IWS1
All Species:
26.06
Human Site:
T693
Identified Species:
44.1
UniProt:
Q96ST2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96ST2
NP_060439.2
819
91955
T693
S
R
P
I
F
G
L
T
S
N
Y
K
G
M
T
Chimpanzee
Pan troglodytes
XP_001139705
1089
121835
T963
S
R
P
I
F
G
L
T
S
N
Y
K
G
M
T
Rhesus Macaque
Macaca mulatta
XP_001087787
827
93220
T701
S
R
P
I
F
G
L
T
S
N
Y
K
G
M
T
Dog
Lupus familis
XP_533312
832
93567
T706
S
R
P
I
F
G
L
T
S
N
Y
K
G
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C1D8
766
85230
R654
T
R
E
E
R
E
Q
R
D
L
E
Q
M
P
Q
Rat
Rattus norvegicus
Q3SWT4
764
85429
E651
G
M
T
R
E
E
R
E
Q
R
D
L
E
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510535
927
102715
T801
S
R
P
I
F
G
L
T
S
N
Y
K
G
M
T
Chicken
Gallus gallus
XP_422571
689
77823
Q577
M
T
R
E
E
R
E
Q
R
D
L
E
Q
M
P
Frog
Xenopus laevis
Q6DE96
836
92684
T710
S
R
P
I
F
G
L
T
S
N
Y
K
G
M
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097000
820
90557
S694
A
R
P
I
F
N
V
S
C
N
F
S
A
M
S
Honey Bee
Apis mellifera
XP_624549
770
87091
M658
A
L
S
K
E
E
R
M
Q
R
D
L
E
Q
T
Nematode Worm
Caenorhab. elegans
Q19375
511
57235
K399
S
R
M
P
E
K
R
K
K
K
I
N
S
R
D
Sea Urchin
Strong. purpuratus
XP_798740
798
90991
E673
S
R
P
I
F
G
V
E
S
N
F
R
S
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06505
410
46064
D298
R
P
I
I
G
A
S
D
N
Y
R
D
K
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
94.3
93.8
N.A.
84.7
82.4
N.A.
69.6
65
60.4
N.A.
N.A.
26.5
30.1
22.7
31.5
Protein Similarity:
100
74.8
96.1
95.3
N.A.
88.4
87.1
N.A.
75.8
73.7
72.9
N.A.
N.A.
46.7
48.8
37.3
50.9
P-Site Identity:
100
100
100
100
N.A.
6.6
0
N.A.
100
6.6
100
N.A.
N.A.
40
6.6
13.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
20
0
N.A.
100
20
100
N.A.
N.A.
73.3
13.3
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
8
15
8
0
0
8
% D
% Glu:
0
0
8
15
29
22
8
15
0
0
8
8
15
0
0
% E
% Phe:
0
0
0
0
58
0
0
0
0
0
15
0
0
0
0
% F
% Gly:
8
0
0
0
8
50
0
0
0
0
0
0
43
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
65
0
0
0
0
0
0
8
0
0
8
8
% I
% Lys:
0
0
0
8
0
8
0
8
8
8
0
43
8
0
0
% K
% Leu:
0
8
0
0
0
0
43
0
0
8
8
15
0
0
0
% L
% Met:
8
8
8
0
0
0
0
8
0
0
0
0
8
58
8
% M
% Asn:
0
0
0
0
0
8
0
0
8
58
0
8
0
0
0
% N
% Pro:
0
8
58
8
0
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
8
8
15
0
0
8
8
15
8
% Q
% Arg:
8
72
8
8
8
8
22
8
8
15
8
8
0
15
0
% R
% Ser:
58
0
8
0
0
0
8
8
50
0
0
8
15
0
15
% S
% Thr:
8
8
8
0
0
0
0
43
0
0
0
0
0
0
50
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
43
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _