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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2S1
All Species:
19.39
Human Site:
Y220
Identified Species:
60.95
UniProt:
Q96SQ9
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SQ9
NP_085125.1
504
55817
Y220
S
S
Q
G
G
Q
T
Y
E
M
F
S
W
F
L
Chimpanzee
Pan troglodytes
XP_001147443
494
56509
Y220
S
T
P
W
A
Q
L
Y
D
M
Y
S
G
I
M
Rhesus Macaque
Macaca mulatta
XP_001100761
494
56465
Y220
S
T
P
W
A
Q
L
Y
D
M
Y
S
G
I
M
Dog
Lupus familis
XP_541605
494
54306
Y219
S
S
P
W
G
Q
T
Y
E
M
F
S
W
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBX6
501
55613
Y221
S
S
P
W
G
Q
A
Y
E
M
F
S
W
L
L
Rat
Rattus norvegicus
P20812
494
56492
Y220
A
T
S
T
G
Q
L
Y
E
M
F
S
S
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P20678
491
56467
Y219
N
R
I
Q
T
Q
L
Y
N
F
F
P
T
I
L
Frog
Xenopus laevis
NP_001085245
496
56377
Y222
S
S
V
W
G
Q
L
Y
N
I
F
P
K
V
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50
50.5
80.7
N.A.
77.9
48.6
N.A.
N.A.
43.8
47.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.8
68.8
87.5
N.A.
88
67.8
N.A.
N.A.
61.9
66
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
33.3
80
N.A.
73.3
46.6
N.A.
N.A.
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
60
80
N.A.
73.3
66.6
N.A.
N.A.
33.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
25
0
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
13
75
0
0
13
0
% F
% Gly:
0
0
0
13
63
0
0
0
0
0
0
0
25
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
13
0
0
0
38
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
0
0
0
0
0
0
63
0
0
0
0
0
0
25
50
% L
% Met:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
50
% M
% Asn:
13
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% N
% Pro:
0
0
50
0
0
0
0
0
0
0
0
25
0
0
0
% P
% Gln:
0
0
13
13
0
100
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
75
50
13
0
0
0
0
0
0
0
0
75
13
0
0
% S
% Thr:
0
38
0
13
13
0
25
0
0
0
0
0
13
0
0
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
0
0
25
0
% V
% Trp:
0
0
0
63
0
0
0
0
0
0
0
0
38
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _