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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WRNIP1 All Species: 21.82
Human Site: S518 Identified Species: 34.29
UniProt: Q96S55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S55 NP_064520.2 665 72133 S518 R G S D Q N A S L Y W L A R M
Chimpanzee Pan troglodytes XP_001159632 665 72086 S518 R G S D Q N A S L Y W L A R M
Rhesus Macaque Macaca mulatta XP_001090684 665 72184 S518 R G S D Q N A S L Y W L A R M
Dog Lupus familis XP_535865 427 47458 S306 R R L V R F A S E D I G L A D
Cat Felis silvestris
Mouse Mus musculus Q91XU0 660 71775 S513 R G S D Q N A S L Y W L A R M
Rat Rattus norvegicus Q8CG07 660 71915 S513 R G S D Q N A S L Y W L A R M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510043 468 51745 S347 R R L V R F A S E D V G L A D
Chicken Gallus gallus XP_418979 562 61303 S441 R R L V R F A S E D I G L A D
Frog Xenopus laevis NP_001089187 572 62408 L451 P L Y V A R R L V R F A S E D
Zebra Danio Brachydanio rerio NP_998085 546 59562 D425 L V R F A S E D I G L A D P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392908 494 55235 V373 N Y I A R R L V R M A C E D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795793 672 73552 D520 I T I D Q I R D S L Q R S H I
Poplar Tree Populus trichocarpa XP_002316599 553 59887 G432 R F A S E D V G L A D P L A L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173839 525 57378 Q404 A D P S A L T Q A V A C Y Q A
Baker's Yeast Sacchar. cerevisiae P40151 587 66526 K465 A A H D A V M K V G L P E A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 63.1 N.A. 95.3 95 N.A. 53.6 63.6 56.6 56.2 N.A. N.A. 39.2 N.A. 38.2
Protein Similarity: 100 99.5 99.8 63.9 N.A. 97.2 96.8 N.A. 60.7 71.8 68.4 65.7 N.A. N.A. 52.7 N.A. 55.2
P-Site Identity: 100 100 100 20 N.A. 100 100 N.A. 20 20 0 0 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 26.6 26.6 20 20 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: 39.7 N.A. N.A. 39.7 35.4 N.A.
Protein Similarity: 51.1 N.A. N.A. 52.7 50.2 N.A.
P-Site Identity: 13.3 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 40 N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 7 7 27 0 54 0 7 7 14 14 34 34 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % C
% Asp: 0 7 0 47 0 7 0 14 0 20 7 0 7 7 34 % D
% Glu: 0 0 0 0 7 0 7 0 20 0 0 0 14 7 0 % E
% Phe: 0 7 0 7 0 20 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 34 0 0 0 0 0 7 0 14 0 20 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 7 0 14 0 0 7 0 0 7 0 14 0 0 0 14 % I
% Lys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % K
% Leu: 7 7 20 0 0 7 7 7 40 7 14 34 27 0 7 % L
% Met: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 34 % M
% Asn: 7 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 7 0 0 0 0 0 0 0 0 14 0 7 0 % P
% Gln: 0 0 0 0 40 0 0 7 0 0 7 0 0 7 0 % Q
% Arg: 60 20 7 0 27 14 14 0 7 7 0 7 0 34 0 % R
% Ser: 0 0 34 14 0 7 0 54 7 0 0 0 14 0 0 % S
% Thr: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 27 0 7 7 7 14 7 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % W
% Tyr: 0 7 7 0 0 0 0 0 0 34 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _