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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TGS1 All Species: 3.94
Human Site: S89 Identified Species: 7.88
UniProt: Q96RS0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RS0 NP_079107.6 853 96608 S89 L D E S E L D S E A E L M R S
Chimpanzee Pan troglodytes XP_001153796 855 96859 A91 E S E L D S E A E L M R S M G
Rhesus Macaque Macaca mulatta XP_001084320 855 96717 A91 E S E L D S E A E L M R S M G
Dog Lupus familis XP_535077 852 96302 E89 N E L D S E A E L M R S M G L
Cat Felis silvestris
Mouse Mus musculus Q923W1 853 96772 M90 L D S E A K L M R S M G L P I
Rat Rattus norvegicus P85107 850 96027 M90 L D P E A K L M R S M G L P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514237 845 95287 K89 T K I K K K K K K K S Q Q K Y
Chicken Gallus gallus NP_001006389 889 99124 L98 E L M K S M G L P L H F G G H
Frog Xenopus laevis NP_001085693 837 94605 T90 E N E L D S E T E I M L K M G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732316 466 53583
Honey Bee Apis mellifera XP_393721 1059 121093 S282 V S L N D G T S Q S Y K E D V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199139 1449 161467 L290 E V M K D M G L P L S F A R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 93.6 82 N.A. 74 73.5 N.A. 60.2 49.4 48.2 N.A. N.A. 26.1 28.9 N.A. 25.1
Protein Similarity: 100 98.3 95.7 89.2 N.A. 85.8 84.4 N.A. 72.9 65.6 64.7 N.A. N.A. 38.6 46 N.A. 38.8
P-Site Identity: 100 13.3 13.3 6.6 N.A. 13.3 13.3 N.A. 0 0 20 N.A. N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 33.3 33.3 13.3 N.A. 26.6 26.6 N.A. 20 6.6 46.6 N.A. N.A. 0 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 0 9 17 0 9 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 25 0 9 42 0 9 0 0 0 0 0 0 9 0 % D
% Glu: 42 9 34 17 9 9 25 9 34 0 9 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % F
% Gly: 0 0 0 0 0 9 17 0 0 0 0 17 9 17 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % H
% Ile: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 9 % I
% Lys: 0 9 0 25 9 25 9 9 9 9 0 9 9 9 0 % K
% Leu: 25 9 17 25 0 9 17 17 9 34 0 17 17 0 9 % L
% Met: 0 0 17 0 0 17 0 17 0 9 42 0 17 25 0 % M
% Asn: 9 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 17 0 0 0 0 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 9 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 17 0 9 17 0 17 0 % R
% Ser: 0 25 9 9 17 25 0 17 0 25 17 9 17 0 17 % S
% Thr: 9 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % T
% Val: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _