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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PANX1
All Species:
26.36
Human Site:
Y325
Identified Species:
72.5
UniProt:
Q96RD7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RD7
NP_056183.2
426
48059
Y325
L
H
F
K
S
E
G
Y
N
D
L
S
L
Y
N
Chimpanzee
Pan troglodytes
XP_522150
426
48087
Y325
M
H
F
K
S
E
G
Y
N
D
L
S
L
Y
N
Rhesus Macaque
Macaca mulatta
XP_001088479
426
47923
Y325
L
H
F
K
S
E
G
Y
N
D
L
S
L
Y
N
Dog
Lupus familis
XP_849329
426
47856
Y324
L
H
F
Q
S
A
G
Y
S
D
L
S
L
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIP4
426
48234
Y324
L
H
F
K
S
E
G
Y
N
D
L
S
L
Y
N
Rat
Rattus norvegicus
P60570
426
48055
Y324
L
H
F
K
S
E
G
Y
N
D
L
S
L
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513293
535
58984
Y393
L
R
F
K
S
E
E
Y
D
D
L
S
L
Y
H
Chicken
Gallus gallus
XP_001235339
356
40359
E257
S
G
I
L
K
V
Y
E
I
L
P
T
F
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957210
417
46937
D317
Q
F
G
Q
A
T
W
D
D
L
A
L
Y
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.7
84.5
N.A.
86.6
88.2
N.A.
58.5
57.9
N.A.
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.5
90.8
N.A.
95
95.3
N.A.
66.1
67.8
N.A.
73.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
80
N.A.
100
100
N.A.
73.3
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
23
78
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
67
12
12
0
0
0
0
0
0
0
% E
% Phe:
0
12
78
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
12
0
0
0
67
0
0
0
0
0
0
0
0
% G
% His:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
67
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
67
0
0
12
0
0
0
0
0
23
78
12
78
12
12
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
56
0
0
0
0
0
67
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% P
% Gln:
12
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
78
0
0
0
12
0
0
78
0
0
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
78
0
0
0
0
12
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _